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GlossaryTransdermal Delivery (TDDS)

method of administering drugs through the skin for absorption

Transdermal Delivery, also known as Transdermal Drug Delivery, is a method of administering medications through the skin. This system allows drugs to be absorbed directly into the bloodstream, providing a controlled release over time. Common examples include nicotine patches for smoking cessation and hormone replacement therapy patches. This method can improve patient compliance and reduce gastrointestinal side effects compared to oral medications.

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research Advances and Challenges in the Treatment of Skin Diseases with the Transdermal Drug Delivery System

2 citations, August 2023 in “Pharmaceutics”

New skin disease treatments using TDDS are improving but face challenges like side effects and high costs.

research Advances in Transdermal Delivery Systems for Treating Androgenetic Alopecia

July 2025 in “Pharmaceutics”

Transdermal delivery systems show promise for treating hair loss by delivering drugs directly through the skin.

research Biocompatible Nanoparticles and Vesicular Systems in Transdermal Drug Delivery for Various Skin Diseases

151 citations, November 2018 in “International Journal of Pharmaceutics”

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Comparison of Rheological Properties, Follicular Penetration, Drug Release, and Permeation Behavior of a Novel Topical Drug Delivery System and a Conventional Cream

research Comparison of Rheological Properties, Follicular Penetration, Drug Release, and Permeation Behavior of a Novel Topical Drug Delivery System and a Conventional Cream

34 citations, October 2014 in “European journal of pharmaceutics and biopharmaceutics”

The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.

research Recent Advances in Microneedle Composites for Biomedical Applications: Advanced Drug Delivery Technologies

64 citations, May 2019 in “Materials Science and Engineering: C”

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

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