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6 / 801 results- Did you know PP405 peptides can help protect your follicles from DHT? PP405 is not a peptide and does not block DHT: it is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier, aimed at waking dormant follicles. Its registered Phase 2 trial (NCT06393452) measured safety and tolerability in 78 adults with pattern hair loss; it is not approved and not for sale.
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Research
5 / 417 resultsresearch Isolation of Multipotent Nestin-Expressing Stem Cells Derived from the Epidermis of Elderly Humans and TAT-VHL Peptide-Mediated Neuronal Differentiation of These Cells
In this study, researchers isolated multipotent stem cells from elderly human epidermis and showed that they could differentiate into neurons using TAT-VHL peptide, suggesting potential for regenerative therapies.
research Topical Delivery of Protein and Peptide Using Novel Cell Penetrating Peptide IMT-P8
This study found that IMT-P8, a novel cell-penetrating peptide, effectively facilitated the dermal delivery of proteins and peptides in mouse skin and cell lines, suggesting potential for topical applications in cosmetics and skin diseases.
research Vitamin E TPGS based transferosomes augmented TAT as a promising delivery system for improved transdermal delivery of raloxifene
This study found that formulating raloxifene in nano-lipid carriers significantly enhanced its permeation and cytotoxicity against cancer cells compared to raw raloxifene.
research Reprofiling synthetic glucocorticoid-induced leucine zipper fusion peptide as a novel and effective hair growth promoter
TAT-GILZ peptide promotes hair growth by boosting stem cell activity.
research The transdermal inhibition of melanogenesis by a cell-membrane-permeable peptide delivery system based on poly-arginine
This study found that the 11R-No. 10 peptide, delivered transdermally, significantly inhibited melanogenesis and produced a whitening effect in a UV-induced sun-tanning guinea pig model without cytotoxicity.
Community Join
5 / 1000+ resultscommunity Last Post Before I Switch Back to Finasteride From Dutasteride
The user plans to switch from dutasteride back to finasteride due to worsening hair loss, possibly due to increased scalp testosterone. Others report mixed results with both treatments, showing individual variability.
community Finasteride 4 months way worse then when I started, shed or am I cooked? 19m
A 19-year-old experienced worsening hair loss after 4 months on finasteride, despite initial improvement with minoxidil. The consensus is to continue treatment for at least a year, as shedding is common and often temporary.
community I don’t think my hair loss is caused by DHT – quitting finasteride after 3 months (1 mg). Need opinions
The user plans to stop finasteride after three months, believing hair loss isn't due to DHT, and will continue with oral minoxidil, microneedling, and ketoconazole shampoo. They suspect stress and poor nutrition are the main causes and seek opinions on DHT blockers' effectiveness.
community Finasteride isn’t going to work on the first week, month ffs..
The conversation emphasizes the need for patience when using finasteride for hair loss, as it can take up to 2 years to see maximum results, and results vary from person to person. Some users also discuss dosage adjustments and side effects, highlighting individual differences in response to the treatment.
community Peptide Therapy -> GHK-CU, ZN-Thumulin, PTD-DBM
The conversation is about the use of peptide therapies for hair loss, specifically GHK-CU, ZN-Thymulin, and PTD-DBM. The user is seeking feedback on the effectiveness of these treatments from those who have tried them.
