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research Saliva secretion in engrafted mouse bioengineered salivary glands using taste stimulation

10 citations , January 2014 in “Journal of prosthodontic research”

This study found that while both natural and bioengineered salivary glands showed similar protein concentrations in response to taste stimulation, their protein compositions and amylase concentrations differed, which may affect nerve signal balance.

Discovery of 7-Methoxy-6-[4-(4-Methyl-1,3-Thiazol-2-yl)-1H-Imidazol-5-yl]-1,3-Benzothiazole (TASP0382088): A Potent and Selective Transforming Growth Factor-β Type I Receptor Inhibitor as a Topical Drug for Alopecia

research Discovery of 7-Methoxy-6-[4-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-5-yl]-1,3-benzothiazole (TASP0382088): A Potent and Selective Transforming Growth Factor-β Type I Receptor Inhibitor as a Topical Drug for Alopecia

6 citations , January 2013 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin”

In this study, TASP0382088 showed potent selective inhibition of the ALK5 receptor, significantly reducing Smad2 phosphorylation in mouse skin following topical application.

research Taste disorders and alopecia in myasthenia gravis

5 citations , April 2024 in “BMC Neurology”

The researchers reported that non-motor symptoms like taste disorders and alopecia are associated with myasthenia gravis, particularly in severe cases and those linked to thymoma.

research Androgenetik alopesi olan hastalarda nf kappa b, tnf-alfa, TGF-beta, tiyoredoksin, nitrik oksit, total oksidan status (TOS), total antioksidan status (TAS) düzeyleri ve tiyol disülfid homeostazisinin araştırılması

January 2019 in “AYBU AVESIS”

In this study, individuals with androgenetic alopecia showed higher serum levels of oxidative stress markers and lower levels of antioxidants, indicating disrupted redox balance and suggesting oxidative stress may accelerate hair loss.

research Pharmacologically altered Androgens, Brain Activation and Response Inhibition in a Stop-Signal Task in Male Heavy Drinkers

January 2026

In this study, lower dihydrotestosterone and higher testosterone levels were linked to increased brain activation during response inhibition, although no behavioral changes were detected.

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Community Join

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community Shouldn’t it be impossible for dutasteride to make hair loss worse?

in Finasteride/Dutasteride 39 upvotes 2 years ago

Dutasteride is unlikely to worsen hair loss; shedding is often temporary. Other factors like inconsistent use, placebo effect, or additional treatments may influence perceived results.

community Recently my cum taste weird and

in Satire 124 upvotes 1 year ago

Dutasteride may alter the taste of semen. Some users report changes in taste while on finasteride or dutasteride.

community Naturally high T (1,100+) causing diffuse thinning while on Dut

22 upvotes 5 months ago

A 26-year-old male with high testosterone is experiencing diffuse hair thinning despite using a comprehensive treatment regimen including dutasteride, oral minoxidil, RU58841, ketoconazole shampoo, microneedling, and low-level laser therapy. Suggestions include adjusting dutasteride dosage, monitoring iron levels, and consulting a dermatologist for further evaluation.

community Why don’t more people use hair fibers?

in Product 527 upvotes 10 months ago

Hair fibers can effectively cover thinning hair when used with minoxidil and hairspray but require daily application and can be inconvenient in certain conditions. Some users prefer treatments like finasteride, dutasteride, microneedling, or wigs due to the maintenance and limitations of hair fibers.

community Why isn’t scalp micropigmentation (SMP) more popular?

in SMP 43 upvotes 1 year ago

Scalp micropigmentation (SMP) is a debated hair loss solution, with some praising its natural look and low maintenance, while others criticize it for looking unnatural and being a temporary fix. Many prefer traditional hair restoration methods like hair transplants or medications such as finasteride and minoxidil.

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Learn

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learn Hair Transplant

What is the success rate of hair transplants? Hair transplants generally have a high success rate, but results can vary.
What is the graft survival rate in hair transplants? Graft survival rates in hair transplants typically range from 90% to 95%.
When will I see results from a hair transplant? Full results from a hair transplant are typically visible between 9 and 18 months.

learn Scalp Micropigmentation

How do I choose the right hairline for scalp micropigmentation? Collaborate with your provider to design a hairline that suits your facial features.

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