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GlossaryTransit Amplifying Cells (TACs)

cells derived from stem cells that rapidly divide before specializing

Transit Amplifying Cells (TACs) are a type of progenitor cell that arise from stem cells and undergo a limited number of rapid divisions before differentiating into specialized cells. In the context of hair biology, TACs play a crucial role in the hair growth cycle by proliferating to produce the cells that form the hair shaft and surrounding structures.

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research Emerging Roles of Transit-Amplifying Cells in Tissue Regeneration and Cancer

32 citations, July 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology”

Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.

research Activation of mTORC1 Signaling Is Required for Timely Hair Follicle Regeneration from Radiation Injury

12 citations, October 2017 in “Radiation Research”

mTORC1 signaling needed for quick hair follicle recovery after radiation damage.

Prostaglandin E2 Prevents Radiotherapy-Induced Alopecia by Attenuating Transit Amplifying Cell Apoptosis Through Promoting G1 Arrest

research Prostaglandin E2 Prevents Radiotherapy-Induced Alopecia by Attenuating Transit Amplifying Cell Apoptosis Through Promoting G1 Arrest

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Prostaglandin E2 helps prevent hair loss from radiotherapy by protecting hair growth cells and aiding self-repair.

research Thymic Stromal Lymphopoietin Controls Hair Growth

July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Thymic stromal lymphopoietin (TSLP) promotes hair growth by stimulating specific skin cells.

research Novel Protective Effect of Prostaglandin for Timely Hair Follicle Regeneration from Radiation Injury

April 2018 in “Radiotherapy and Oncology”

Prostaglandin helps regenerate hair follicles after radiation damage.

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