19 citations
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March 1997 in “Journal of Cutaneous Pathology” This study observed that patients with alopecia areata often have a T-cell receptor repertoire in skin lesions that suggests a specific antigen-driven immune response may be important in the disease's pathogenesis.
This study found that γδTregs can prevent and treat alopecia areata in a mouse model with human scalp transplants, suggesting potential for cell-based therapies in autoimmune diseases like alopecia.
April 2020 in “International Journal of Dermatology” This study found that peribulbar lymphocytic infiltration can effectively differentiate between alopecia areata and androgenetic alopecia using T-cell infiltration patterns in skin tissue.
7 citations
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October 1988 in “Clinics in Dermatology” Minoxidil may help hair regrowth in alopecia areata by affecting T-cells.
18 citations
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January 2017 in “Annals of dermatology/Annals of Dermatology” This study found that Th17 lymphocytes may play a more crucial role than cytotoxic T cells in the development of alopecia areata due to their infiltration around the hair bulb/bulge, which exacerbates hair loss as histopathological grade worsens.