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In this report, the sighting of a maned wolf in a rural area of Brazil with severe hair loss, likely due to alopecia, was documented, and it was suspected that the condition resulted from disease transmission from domestic dogs.

This report describes the first diagnosed case of dermatophytosis caused by Microsporum canis in a young maned wolf, emphasizing the importance of monitoring emerging diseases in this vulnerable species.

This review discusses the roles of metabolism, reactive oxygen species, intracellular pH, and cell morphology in influencing cell fate decisions during stem cell differentiation but reports no new experimental results.

In this study, researchers investigated GAGs from the marine invertebrate Microcosmus exasperatus, finding that its polysaccharides possess antitumoral properties without affecting anticoagulant activity. The unique composition shows potential for cancer treatment when combined with existing therapies in future studies.

This review detailed the significant progress and challenges in the design and application of PROTACs, a novel class of cancer therapeutics, highlighting their clinical trials, design complexities, and the role of artificial intelligence in improving their efficacy and selectivity for cancer therapy.