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Glossary Sézary syndrome

rare, aggressive skin cancer involving malignant T-cells

Sézary syndrome is a rare and aggressive form of cutaneous T-cell lymphoma, a type of cancer that originates in the T-lymphocytes (a kind of white blood cell) and primarily affects the skin. It is characterized by the presence of cancerous T-cells in the blood, skin, and lymph nodes, leading to symptoms such as red, itchy, and scaly skin, enlarged lymph nodes, and sometimes hair loss.

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research The spectrum of hair loss in patients with mycosis fungoides and Sézary syndrome

39 citations , October 2010 in “Journal of The American Academy of Dermatology”

This study reported that alopecia occurred in 2.5% of patients with mycosis fungoides or Sézary syndrome, with some cases resembling alopecia areata and others associated with specific skin lesions.

Follicular Mucinosis in Association with Sézary Syndrome

research Follicular mucinosis in association with Sezary syndrome

17 citations , May 1987 in “Clinical and Experimental Dermatology”

This study reports a new association of follicular mucinosis occurring in a patient with Sézary syndrome.

research An occurrence of eosinophilic folliculitis and alopecia associated with a sustained complete response to mogamulizumab in Sézary syndrome: a case report

5 citations , January 2024 in “Therapeutic Advances in Hematology”

This report suggests an association between eosinophilic folliculitis and sustained complete response in a Sézary syndrome patient treated with mogamulizumab, although regular monitoring is necessary to prevent relapse.

Characteristics Associated with Significantly Worse Quality of Life in Mycosis Fungoides/Sézary Syndrome from the Prospective Cutaneous Lymphoma International Prognostic Index (PROCLIPI) Study

research Characteristics associated with significantly worse quality of life in mycosis fungoides/Sézary syndrome from the Prospective Cutaneous Lymphoma International Prognostic Index ( PROCLIPI ) study

67 citations , May 2019 in “British Journal of Dermatology”

In this study, newly diagnosed women with mycosis fungoides or Sézary syndrome and those with alopecia experienced significantly poorer health-related quality of life.

Dermoscopy: 4th Conference of the Section of Dermoscopy and Other Skin Imaging Techniques of the Polish Dermatological Society - Abstracts

research Dermoscopy — 4th Conference of the Section of Dermoscopy and Other Skin Imaging Techniques (DiTOS) of the Polish Dermatological Society — Abstracts

January 2026 in “Forum Dermatologicum”

This study observed that 2.5% of patients with mycosis fungoides or Szary syndrome experienced alopecia, predominantly within skin lesions, with scalp metastases from other cancers also potentially causing hair loss, highlighting the diagnostic value of trichoscopy in differentiating alopecia types.

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community So it turns out Post Finasteride Syndrome was never real?

in Finasteride/Dutasteride 271 upvotes 2 years ago

Post Finasteride Syndrome (PFS) is debated, with some users reporting severe side effects from finasteride, while others believe these effects are rare or psychosomatic. Treatments discussed include finasteride, minoxidil, and RU58841.

community Why is Finasteride seen as “scary” for men, but hormonal birth control is totally normalized for women?

in Finasteride/Dutasteride 757 upvotes 1 year ago

Finasteride is seen as risky for men due to side effects like erectile dysfunction, while hormonal birth control for women is normalized despite its side effects. The discussion points out a double standard influenced by societal and gender norms.

community Trying to understand finasteride side effects and post finasteride syndrome

70 upvotes 5 years ago

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

community risks with finasteride and dutasteride

138 upvotes 1 year ago

Finasteride and dutasteride have potential risks, including post-finasteride syndrome, but are commonly used for hair loss. RU58841, minoxidil, and needling are suggested as alternatives, though all treatments carry risks.

community The truth about Dutasteride (w/ sources)

in Finasteride/Dutasteride 52 upvotes 3 years ago

The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.

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