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a topical anti-androgen with less systemic involvement
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5 / 14 resultslearn Pyrilutamide
highly targeted anti-androgen that might have minimal systemic effects
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a synthetic estrogen used topically as an anti-androgen
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learn Finasteride
Frontline, gold standard treatment for combatting androgenic alopecia
Research
5 / 1000+ resultsresearch Fulminant Systemic Vasculitis in Systemic Lupus Erythematosus: Case Report and Review of the Literature
Early diagnosis and quick treatment are crucial for severe lupus cases.
research Skin Manifestations Associated With Systemic Diseases – Part I
The conclusion is that early diagnosis of skin signs linked to diseases like Lupus, Dermatomyositis, and Rheumatoid Arthritis is crucial to prevent serious complications.
research Herpes Zoster Precipitating First Attack of Neuromyelitis Optica Along with Perinuclear Anti-Neutrophilic Cytoplasmic Antibody Positive Vasculitis
A woman's shingles infection triggered her first episode of a rare neurological disorder and blood vessel inflammation.
research Comprehensive Overview of Rheumatology Studies: Ottawa, Ontario, Canada, February 13–16, 2013
The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.
research The British Society for Rheumatology Guideline for the Management of Systemic Lupus Erythematosus in Adults
The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.
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5 / 1000+ resultscommunity A Systemic Review on Topical Marketed Formulations, Natural Products, and Oral Supplements to Prevent Androgenic Alopecia: A Review
Topical formulations, natural products, and CAM therapies are being used to treat Androgenic alopecia to avoid side effects of Finasteride and Minoxidil. The review covers various low-risk, alternative treatment options.
community How much Minoxidil goes systemic?
The conversation is about the systemic absorption of Minoxidil and the potential switch from topical to oral Minoxidil due to its effectiveness. The user considers oral Minoxidil after experiencing no side effects from a year of using 15% topical Minoxidil.
community Does ketoconazole reduce systemic DHT by much?
Ketoconazole shampoo does not significantly reduce systemic or scalp DHT levels and is mainly used for its anti-fungal and anti-inflammatory effects. It is not a replacement for finasteride, which is recommended by some users despite concerns about side effects.
community Efficacy and Systemic DHT Suppression of Topical Finasteride vs Dutasteride
Topical dutasteride may have limited absorption due to its higher molecular mass compared to finasteride, potentially affecting its efficacy in suppressing DHT locally. Microneedling might enhance dutasteride absorption, possibly offering stronger local DHT suppression with fewer systemic effects.
community If PP405 goes systemic this would be quite catastrophic
Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.