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research Viral-Associated Trichodysplasia of Immunosuppression

40 citations , August 2010 in “Archives of dermatology”

This case report describes the youngest known patient with viral-associated trichodysplasia of immunosuppression, where systemic valganciclovir therapy improved facial papule eruptions following cardiac transplantation.

research Dermatoscopy case of the month: Trichodysplasia spinulosa

2 citations , September 2021 in “JAAD case reports”

This report describes a case of trichodysplasia spinulosa in a renal transplant patient, characterized by unique dermatoscopic features and highlighting the need for timely diagnosis.

research Trichodysplasia of immunosuppression treated with oral valganciclovir

41 citations , December 2008 in “Journal of the American Academy of Dermatology”

This review discusses fixed drug eruption (FDE) potentially linked to finasteride and emphasizes dermatologists' need to recognize its possible occurrence due to the drug's widespread use, but reports no new clinical results.

research Safety of dermatologic medications in pregnancy and lactation

73 citations , March 2014 in “Journal of The American Academy of Dermatology”

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

research Skin disease in pregnancy

34 citations , June 2014 in “The BMJ”

This study found that children with intracranial injuries had significantly lower odds of achieving satisfactory early academic performance compared to those without head injuries.

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community Non-systemic hair loss stack, is there any hope?

6 upvotes 3 weeks ago

A 19-year-old is experiencing hair thinning and has tried various doses of oral and topical finasteride but faced psychological and sexual side effects. They are considering topical anti-androgens like KX826, ketoconazole cream, and RU58841 as alternatives, while others suggest clascoterone and topical dutasteride.

community Minimizing systemic DHT reduction with topicals

5 upvotes 1 month ago

The conversation discusses minimizing systemic DHT reduction using topical treatments for hair loss, specifically mentioning Minoxidil, Finasteride, and a proprietary carrier for DUT by XYON Health. The focus is on finding effective DHT blockers with minimal systemic absorption.

community Has any data on systemic absorption of pyrilutamide been published?

1 upvotes 4 months ago

Pyrilutamide shows minimal systemic absorption with low plasma levels and no accumulation, suggesting it's unlikely to cause systemic side effects. However, full results are not yet published in scientific journals.

community Any treatment not nuking systemic DHT levels?

16 upvotes 7 months ago

Hair loss treatments that avoid significantly lowering systemic DHT levels, focusing on topical options like dutasteride mesotherapy, minoxidil, and ketoconazole. The user is exploring alternatives like KX-826 and RU58841 due to concerns about hormone levels.

community Are we underestimating systemic absorption with homemade/generic Topical Fin? (HPCH vs. PG/Ethanol formulations)

5 upvotes 7 months ago

Topical finasteride may have higher systemic absorption and lower efficacy when using a Propylene Glycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.

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Learn

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learn Follistatin

Can follistatin be applied topically, or is it only effective through injections or systemic use? Follistatin is not effective when applied topically and requires injections or systemic use.

learn Thymosin Beta 4

Is Thymosin Beta 4 being explored more as a topical treatment or as a systemic (oral or injectable) approach for hair loss? Thymosin Beta 4 is primarily being explored as a topical treatment for hair loss.

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