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research Quality of Life, Burden of Disease, Co-morbidities, and Systemic Effects in Vitiligo Patients

79 citations , March 2017 in “Dermatologic clinics”

This review discusses the complex systemic nature of vitiligo and its associations with autoimmune conditions, emphasizing the need for increased understanding and awareness of related comorbidities and psychological effects.

Adolescent Androgenic Alopecia: Pathophysiology, Diagnosis, and Treatment

research Adolescent androgenic alopecia.

1 citations , October 2011 in “PubMed”

This review discusses the pathophysiology, diagnosis, and treatment of adolescent androgenic alopecia and reports no new clinical results.

research Lichen planopilaris in a Latin American (Chilean) population: demographics, clinical profile and treatment experience

19 citations , July 2017 in “Clinical and experimental dermatology”

This study provides one of the first descriptions of the demographic, clinical, and therapeutic characteristics of lichen planopilaris in Chilean adults, reporting that treatment usually reduced or halted disease progression.

Reversal of Advanced Androgenetic Alopecia Through Individualized Classical Homeopathy and Exosomes Therapy at Dr Batra’s Homeopathy Clinic

research Reversal of Advanced Androgenetic Alopecia Through Individualized Classical Homeopathy & Exosomes Therapy at Dr Batra’s® Homeopathy Clinic

January 2026 in “Medico Research Chronicles”

This case study reported that a male patient with advanced androgenetic alopecia showed sustained improvements in hair density and quality of life after receiving individualized homeopathic treatment and regenerative hair therapy.

research Insights into disparities observed with COVID‐19

147 citations , November 2020 in “Journal of Internal Medicine”

This review discusses factors contributing to COVID-19 severity disparities, highlighting age, comorbidities, race/ethnicity, and gender, and reports no new clinical findings; it emphasizes understanding these mechanisms to address risk differences.

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community Non-systemic hair loss stack, is there any hope?

6 upvotes 2 weeks ago

A 19-year-old is experiencing hair thinning and has tried various doses of oral and topical finasteride but faced psychological and sexual side effects. They are considering topical anti-androgens like KX826, ketoconazole cream, and RU58841 as alternatives, while others suggest clascoterone and topical dutasteride.

community Minimizing systemic DHT reduction with topicals

5 upvotes 3 weeks ago

The conversation discusses minimizing systemic DHT reduction using topical treatments for hair loss, specifically mentioning Minoxidil, Finasteride, and a proprietary carrier for DUT by XYON Health. The focus is on finding effective DHT blockers with minimal systemic absorption.

community Has any data on systemic absorption of pyrilutamide been published?

1 upvotes 4 months ago

Pyrilutamide shows minimal systemic absorption with low plasma levels and no accumulation, suggesting it's unlikely to cause systemic side effects. However, full results are not yet published in scientific journals.

community Any treatment not nuking systemic DHT levels?

16 upvotes 6 months ago

Hair loss treatments that avoid significantly lowering systemic DHT levels, focusing on topical options like dutasteride mesotherapy, minoxidil, and ketoconazole. The user is exploring alternatives like KX-826 and RU58841 due to concerns about hormone levels.

community Are we underestimating systemic absorption with homemade/generic Topical Fin? (HPCH vs. PG/Ethanol formulations)

5 upvotes 7 months ago

Topical finasteride may have higher systemic absorption and lower efficacy when using a Propylene Glycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.

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Learn

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learn Follistatin

Can follistatin be applied topically, or is it only effective through injections or systemic use? Follistatin is not effective when applied topically and requires injections or systemic use.

learn Thymosin Beta 4

Is Thymosin Beta 4 being explored more as a topical treatment or as a systemic (oral or injectable) approach for hair loss? Thymosin Beta 4 is primarily being explored as a topical treatment for hair loss.

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