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research Successful treatment with hydroxychloroquine for systemic lupus erythematosus with cutaneous involvement accompanied by a xanthomatous reaction

3 citations , December 2019 in “Lupus”

In this report, researchers describe a case of scalp discoid lupus erythematosus unresponsive to topical treatments, where hydroxychloroquine administered at 200 mg/day led to complete resolution of skin lesions in five months.

research Resolution of Discoid Lupus Alopecia With Systemic Hydroxychloroquine and Topical Pimecrolimus Combination Therapy

June 2024 in “Cureus”

In this case study, a 46-year-old woman with localized discoid lupus erythematosus on her scalp showed significant improvement with a combination of oral hydroxychloroquine and topical pimecrolimus, despite limited success with previous treatments.

research The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults

213 citations , June 2017 in “Rheumatology”

This guideline outlines the management of systemic lupus erythematosus in adults but reports no new clinical findings.

research Lupus erythematosus: systemic and cutaneous manifestations

144 citations , September 2006 in “Clinics in Dermatology”

This article outlines manifestations of systemic lupus erythematosus, noting rapid joint symptom improvement with corticosteroids and antimalarial drug responsiveness for skin symptoms, and links anti-Ro with photosensitive rash and subacute lupus.

research Possible protective effect of hydroxychloroquine on delaying the occurrence of integument damage in lupus: LXXI, data from a multiethnic cohort

58 citations , January 2010 in “Arthritis Care & Research”

In this study, hydroxychloroquine use was associated with a delayed onset of integument damage in SLE patients, while higher disease activity over time predicted quicker damage development.

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learn Hydroxychloroquine sulphate

learn Hydroquinone

learn Follistatin

Can follistatin be applied topically, or is it only effective through injections or systemic use? Follistatin is not effective when applied topically and requires injections or systemic use.

learn Thymosin Beta 4

Is Thymosin Beta 4 being explored more as a topical treatment or as a systemic (oral or injectable) approach for hair loss? Thymosin Beta 4 is primarily being explored as a topical treatment for hair loss.

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community can someone help me identify these pls

in Treatment 9 months ago

The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

community The Worst Hair Loss Condition You (MAY) have: LPP

48 upvotes 2 years ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Non-systemic hair loss stack, is there any hope?

6 upvotes 2 weeks ago

A 19-year-old is experiencing hair thinning and has tried various doses of oral and topical finasteride but faced psychological and sexual side effects. They are considering topical anti-androgens like KX826, ketoconazole cream, and RU58841 as alternatives, while others suggest clascoterone and topical dutasteride.

community Minimizing systemic DHT reduction with topicals

5 upvotes 3 weeks ago

The conversation discusses minimizing systemic DHT reduction using topical treatments for hair loss, specifically mentioning Minoxidil, Finasteride, and a proprietary carrier for DUT by XYON Health. The focus is on finding effective DHT blockers with minimal systemic absorption.

community Has any data on systemic absorption of pyrilutamide been published?

1 upvotes 4 months ago

Pyrilutamide shows minimal systemic absorption with low plasma levels and no accumulation, suggesting it's unlikely to cause systemic side effects. However, full results are not yet published in scientific journals.

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