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Development of a Two-Dimensional Model for Predicting Transdermal Permeation with the Follicular Pathway: Demonstration with a Caffeine Study

research Development of a Two-Dimensional Model for Predicting Transdermal Permeation with the Follicular Pathway: Demonstration with a Caffeine Study

35 citations , June 2017 in “Pharmaceutical research”

This study presented a new two-dimensional model that successfully predicts transdermal permeation of caffeine, highlighting the significant role of the follicular pathway in increasing systemic bioavailability.

research Liposomal systems as drug delivery vehicles for dermal and transdermal applications

151 citations , July 2011 in “Archives of Dermatological Research”

This review discusses various strategies to enhance drug delivery through the skin barrier, highlighting liposomes as promising carriers for increased dermal concentrations in topical therapies, but reports no new research results.

research Key considerations of injectable minoxidil for alopecia

March 2025 in “Archives of Dermatological Research”

This source explores injectable minoxidil as a hair loss treatment, noting its enhanced bioavailability but also the potential for adverse effects and higher costs compared to other formulations, with a call for further research on its efficacy and access relative to alternatives.

Vitamin D in Dermatology and Cosmetology

research Dermatoloji ve Kozmetolojide D Vitamini

June 2022

Vitamin D is crucial for skin health and managing skin diseases.

research Novel natural lipids based NLC containing finasteride improved androgenetic alopecia treatment in rats

October 2024 in “International Journal of Pharmaceutics”

This study found that a topical formulation with nanostructured lipid carriers containing finasteride significantly restored hair follicles in androgenetic alopecia-induced rats without systemic absorption, suggesting its potential for safer and effective AGA treatment.

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community can topical retinol ( vitamin A ) affect hair / hairloss ???

4 upvotes 3 years ago

Topical retinol does not affect hair loss and may help hair regrowth. It is different from isotretinoin, which can cause hair loss due to its systemic effects.

community questions regarding topical finasteride

in Finasteride 4 upvotes 7 years ago

The conversation discusses the potential effectiveness and risks of using topical finasteride for hair loss, with considerations about using DMSO as a vehicle for application. Concerns are raised about DMSO's safety, absorption issues, and the systemic effects of topical finasteride.

community Sublingual Minoxidil - Cure to Hairloss?

in Minoxidil 583 upvotes 2 years ago

The conversation discusses the potential benefits of sublingual minoxidil for hair loss treatment. It suggests that sublingual minoxidil, which bypasses the liver, may have fewer side effects, greater bioavailability, and could be more effective than oral minoxidil.

community Does Tretinoin work? Can somebody share their experience

2 upvotes 7 months ago

Tretinoin can increase hair follicles and is used alongside minoxidil and finasteride for hair growth, though it may cause skin peeling. Users report varying results, with some experiencing regrowth and others questioning its efficacy for hair.

community Is it dumb to use both oral and topical minoxidil

in Minoxidil 6 upvotes 1 year ago

Using both oral and topical minoxidil is not considered dumb, and some users report better results with both, though it may cause shedding and scalp irritation. Combining minoxidil with finasteride is recommended for better effectiveness.

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