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research Topical Application of the Synthetic Triterpenoid RTA 408 Protects Mice from Radiation-Induced Dermatitis

61 citations , April 2014 in “Radiation Research”

This study observed that topically applied RTA 408 reduced the severity of radiation-induced dermatitis in mice, with the highest dose significantly reducing and alleviating skin damage and associated inflammation.

Transcriptome Sequencing and Identification of Cytochrome P450 Monooxygenases Involved in the Biosynthesis of Maslinic Acid and Corosolic Acid in Avicennia Marina

research Transcriptome sequencing and identification of cytochrome P450 monooxygenases involved in the biosynthesis of maslinic acid and corosolic acid in Avicennia marina

10 citations , October 2018 in “Plant Biotechnology”

This study identified two cytochrome P450 enzymes in Avicennia marina leaves that may contribute to the biosynthesis of triterpenoids, potentially responsible for the plant's medicinal properties.

Pentacyclic Triterpenoid Maslinic Acid Promotes Hair Growth Comparable To Minoxidil: A New Insight On The Potential Involvement Of Cilia Activity

research Pentacyclic Triterpenoid Maslinic Acid Promotes Hair Growth Comparable to Minoxidil: A New Insight on the Potential Involvement of Cilia Activity

January 2025 in “Institutional Repositories DataBase (IRDB)”

This study observed that topical application of maslinic acid stimulated hair growth in mice comparably to minoxidil, possibly through the Wnt/β-catenin pathway and involving ciliary gene activity, highlighting increased levels of trichogenic gene expression and protein levels.

research SYSTEMATIC REVIEW ON SYNTHETIC AND HERBAL MEDICATIONS FOR THE TREATMENT OF ALOPECIA

December 2024 in “Asian Journal of Pharmaceutical and Clinical Research”

This study reviews the performance and safety of synthetic medications like minoxidil and finasteride compared to herbal remedies such as saw palmetto for treating alopecia, highlighting the need for more research to better understand their therapeutic roles and optimize patient care.

Synthesis of Cu4O3 Nanoparticles Using Pumpkin Seed Extract: Optimization, Antimicrobial, and Cytotoxicity Studies

research Synthesis of Cu ₄ O ₃ nanoparticles using pumpkin seed extract: Optimization, antimicrobial, and cytotoxicity studies

January 2025 in “Nanotechnology Reviews”

This study reported a green synthesis method for copper oxide nanoparticles using pumpkin seed extract, achieving significant antibacterial activity against Bacillus subtilis and moderate cytotoxic effects against certain cancer cell lines, indicating potential biomedical applications for these eco-friendly nanomaterials.

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learn plant sterol complex

learn sh-Polypeptide-7

Is sh-Polypeptide-7 considered a natural or synthetic ingredient, and how is it typically applied? sh-Polypeptide-7 is a synthetic ingredient applied in hair-care products.

learn Glycerin

What’s the difference between vegetable glycerin and synthetic glycerin in hair products? Vegetable glycerin is plant-derived, while synthetic glycerin is petroleum-based, but both are chemically identical.

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community scientific evidence of the effect of minoxidil on collagen synthesis

in Minoxidil 3 upvotes 11 months ago

Minoxidil may inhibit collagen synthesis at high concentrations, with anecdotal reports of skin aging but limited research. Dermatologists and other specialists show little interest in studying minoxidil's side effects.

community Inhibition of collagen synthesis, oral versus topical minoxidil

4 upvotes 3 years ago

The conversation discusses the use of oral versus topical minoxidil for hairline recession, with concerns about collagen synthesis inhibition. Oral minoxidil may affect collagen production more broadly, while topical minoxidil's effects are localized but may cause skin issues.

community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

3 upvotes 1 year ago

DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

community Has anyone here tried topical synthetic prostaglandins (Bimatoprost, Latanoprost, cetirizine) to stimulate hair growth?

6 upvotes 2 years ago

The conversation discusses using topical synthetic prostaglandins like Bimatoprost, Latanoprost, and cetirizine for hair growth. The user shares a link suggesting these treatments may be effective.

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