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This study found that treating neonatal mice with the neurotoxin 6-OHDA resulted in temporary hair loss and thinner skin compared to control mice, linking sympathetic neurons to hair growth and skin thickness.

This study found that concentrated clusters of noradrenergic nerve fibers form a longitudinal linear system in rat skin, particularly innervating arrector pili muscles.

This review highlights that disturbances in neuroimmune communication, particularly between sympathetic nerves and macrophages, may contribute to autoimmune diseases like rheumatoid arthritis and type 1 diabetes, and suggests potential therapeutic avenues by restoring this communication in preclinical and early clinical studies.

Minoxidil treatment in mice preserved the integrity of elastic lamellae and improved arterial biomechanical properties, especially in females, suggesting it could be an anti-arterial aging agent potentially suitable for female-targeted therapies.

This review discusses recent advancements in understanding how the sympathetic nervous system and norepinephrine regulate hair follicle growth, highlighting innovative studies that explore their effects on hair follicle stem cells.