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research 559 Visualization of sweat suppression following botulinum toxin A by soluble microneedle arrays

April 2016 in “Journal of Investigative Dermatology”

This study found that administering botulinum toxin A via Flex-PADs to mouse footpads inhibited sweating similarly to traditional injections, suggesting a promising patient-friendly delivery method for hyperhidrosis treatment.

research Cylindroma as Tumor of Hair Follicle Origin

57 citations , February 2006 in “Journal of Investigative Dermatology”

Cylindromas likely originate from hair follicle stem cells, not sweat glands.

research 839 Spatiotemporal antagonism in mesenchymal-epithelial Signaling in sweat versus hair fate decision

April 2017 in “Journal of Investigative Dermatology”

This study identified that in mice, sweat gland development is directed by mesenchymal signals that suppress SHH-production, while in humans, this occurs through a BMP spike in embryonic development.

research Involvement of Wnt, Eda and Shh at defined stages of sweat gland development

55 citations , September 2014 in “Development”

In this study, mouse sweat gland development relied on a regulatory sequence initiated by Wnt/β-catenin signaling, and disruptions in Wnt, Eda, or Shh pathways led to distinct developmental failures.

Label Retaining Cells with Myoepithelial Characteristics from the Proximal Acinar Region Define Stem Cells in the Sweat Gland

research Label Retaining Cells (LRCs) with Myoepithelial Characteristic from the Proximal Acinar Region Define Stem Cells in the Sweat Gland

36 citations , September 2013 in “PLoS ONE”

This study found that sweat gland stem cells primarily maintain sweat gland homeostasis but can trans-differentiate to aid in epidermal healing and regenerate diverse skin structures under certain conditions.

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Community Join

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community DUT 3 times a week is the holy grail sweet spot, better than FIN every day.

6 upvotes 4 years ago

User "logart89" claims DUT 3 times a week is better than daily FIN for hair loss. Their routine includes DUT, topical DUT, stemoxydine and alfatradiol mix, 5% minoxidil with tretinoin, and weekly derma stamping.

community Finasteride and “anti-aging” effects

in Treatment 218 upvotes 1 year ago

Finasteride may help users look younger by suppressing DHT, affecting skin and hair. Users also emphasize skincare, sunscreen, and lifestyle for maintaining a youthful appearance.

community Research Backed Dutasteride Simulator (Serum/Scalp DHT included for all doses)

116 upvotes 1 year ago

A dutasteride simulator predicts that daily 0.5 mg dosing results in higher DHT suppression compared to less frequent dosing. Twice-weekly dutasteride may be as effective as finasteride 5 mg, providing a balance between efficacy and ease of use.

community Can I take finasteride and creatine both daily?

20 upvotes 2 years ago

Creatine may accelerate genetic hair loss, but stopping it can reverse the effects. Finasteride helps block DHT, and some users report no issues taking both daily.

community Dutasteride and minoxidil : 5 months

in Is this regrowth? 88 upvotes 10 months ago

The user is using dutasteride and minoxidil foam for hair regrowth, applying minoxidil once daily due to side effects from the liquid form. They plan to increase dutasteride dosage and possibly apply minoxidil twice daily, while also using ciclopirox olamine shampoo and sulfur soap.

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learn sweet almond

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