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research The Microanatomy of Human Skin in Aging

5 citations , April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that by using an automated system to analyze skin histology, 108 structural features were significantly affected by age, and it identified four new aging biomarkers and notable sex-based differences in skin aging.

research A Composite Model for the Transport of Hydrophilic and Lipophilic Compounds Across the Skin: Steady-State Behavior

32 citations , September 2018 in “Journal of pharmaceutical sciences”

This study extended a skin diffusion model to include a porous pathway, effectively explaining the permeability of both polar and lipophilic solutes through the stratum corneum.

research Penetration and Distribution in Human Skin Focusing on the Hair Follicle

1 citations , July 2005 in “CRC Press eBooks”

This paper discusses topical drug delivery targeting the pilosebaceous unit for skin diseases and cosmetic purposes, emphasizing formulation choice and drug physicochemical properties but reports no new findings.

research 0932 Spatiotemporal gradient of mesenchymal stiffness controls sweat gland morphogenesis

July 2026 in “Journal of Investigative Dermatology”

Tissue stiffness affects sweat gland development by guiding cell differentiation through specific signals.

Sweat Glands Shrink Upward With Aging, Causing Dermal Layer Defects Leading to Loss of Skin Elasticity and Wrinkling - Establishment of 3D Imaging Method for Skin Appendages

research 250 Sweat glands shrink upward with aging, causing dermal layer defects that lead to loss of skin elasticity and wrinkling-establishment of 3D imaging method for skin appendages

September 2017 in “Journal of Investigative Dermatology”

This study found that their novel 3D-imaging method, ASAXA-μCT, identified shrinkage of sweat glands as a key factor in skin aging, which leads to dermal defects, decreased elasticity, and increased wrinkling and sagging.

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community now exactly 2 years since starting 1mg oral fin

in Progress Pictures 749 upvotes 1 year ago

The user experienced significant hair regrowth using 1mg oral finasteride daily and recently added minoxidil 5% to address remaining gaps. They reported no significant side effects, attributing any perceived changes to weight fluctuations rather than the medication.

community Can I take finasteride and creatine both daily?

20 upvotes 2 years ago

Creatine may accelerate genetic hair loss, but stopping it can reverse the effects. Finasteride helps block DHT, and some users report no issues taking both daily.

community Fin and Oral Minoxidil completely changed my hair texture (8months progress)

in Progress Pictures 353 upvotes 2 years ago

Finasteride and oral minoxidil significantly improved hair texture and thickness over 8 months. The user also experienced increased hair growth on the beard and eyebrows.

community Does finasteride decrease free testosterone?

in Research/Science 186 upvotes 1 year ago

Finasteride may decrease free testosterone by increasing SHBG, potentially causing side effects like reduced libido and hormonal changes. Some find it effective for hair loss, while others experience negative effects.

community 6 month post-transplant, Dr Carman MD surgeon

5 upvotes 3 years ago

A user shared their positive experience with a hair transplant performed by Dr. Timothy Carman, using 1100 grafts via FUT surgery, and reported satisfaction with the results and minimal scarring. The user continues to use minoxidil and finasteride for hair maintenance.

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learn Epidermal Growth Factor

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