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research The combination of hair follicle-specific marker LHX2 and co-expressed marker can distinguish between sweat gland placodes and hair placodes in rat

5 citations , September 2021 in “Journal of Molecular Histology”

In this study, the researchers identified LHX2 as a specific marker for hair follicle placodes, differentiating them from eccrine sweat gland placodes through double immunofluorescence staining.

research 439 Gradients of Mesenchymal Stiffness Control Sweat Gland Cell Fate Specification During Morphogenesis

November 2025 in “Journal of Investigative Dermatology”

Mesenchymal stiffness affects sweat gland cell development.

research 1439 Development of a complex skin organ in human induced pluripotent stem cell-derived organoids

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study developed protocols to create skin organoids with hair follicles and other appendages from human induced pluripotent stem cells, representing a significant step towards understanding hair follicle development and potential applications in modeling skin diseases and reconstructive surgeries.

research Morphological and functional analysis on M3R mediated sweating in TSC1 k/o mouse

August 2019

In this study, Sox13 was identified as a novel marker for early hair follicle development and differentiation in mice, though it appears to be dispensable for overall epidermal and adnexal development.

research Ectodysplasin Signaling in Cutaneous Appendage Development: Dose, Duration, and Diversity

9 citations , March 2009 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study reports that the maintenance and morphogenesis of skin appendages rely on both the dose and duration of ectodysplasin signaling.

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community I’ve catch my hair loss early and I’m glad I took the measures to prevent it

in Chat 1 year ago

The conversation discusses a 17-year-old using finasteride to address early hair thinning, expressing pride in taking action to prevent hair loss. The user emphasizes the importance of starting treatment early and shares experiences with the hair loss community.

community Not sure if it's in my head or not but I swear Nizoral 2% has made my hair thicker

in Ketoconazole 45 upvotes 1 year ago

The user noticed thicker hair and reduced dandruff after using Nizoral 2% (ketoconazole) every few days, alongside topical minoxidil 5% for over a year. They plan to reduce Nizoral use to once a week to avoid scalp irritation.

community Hot weather causing hair shedding?

3 upvotes 9 months ago

Hot weather can increase hair shedding, possibly due to dehydration and active sebaceous glands. Using shampoos with salicylic acid or zinc pyrithione may help; daily anti-inflammatory use is not recommended.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

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