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research Sulfotransferases, Sulfatases, and Formylglycine-Generating Enzymes: A Sulfation Fascination

83 citations, July 2008 in “Current Opinion in Chemical Biology”

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

research Enzymatic and Non-Enzymatic Sulfation Mechanisms in the Biological Actions of Minoxidil

53 citations, January 1993 in “Biochemical Pharmacology”

Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.

research Sulfation of Minoxidil by Multiple Human Cytosolic Sulfotransferases

59 citations, February 1998 in “Chemico-Biological Interactions”

Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.

research Biology of Human Hair: Know Your Hair to Control It

13 citations, January 2010 in “Advances in Biochemical Engineering / Biotechnology”

Understanding hair biology is key to developing better treatments for hair and scalp issues.

research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition

451 citations, March 2005 in “Endocrine Reviews”

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

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community Sugars ARE important for hair growth | Glycosaminoglycans as Hair Growth Stimulant

in Research/Science 75 upvotes 4 months ago

Glycosaminoglycans are important for hair growth, and combining minoxidil with tretinoin and Biopeptide-CL may enhance hair growth by boosting glycosaminoglycan levels and improving the hair follicle environment. Users discussed the potential effectiveness and future of these treatments.

community Comprehensive Microneedling Guide

in Microneedling 290 upvotes 2 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community How is it possible for someone to be a non responder to ORAL minoxidil?

in Minoxidil 66 upvotes 8 months ago

Some individuals do not respond to oral minoxidil for hair loss, despite it generally working by improving blood flow to hair follicles. Factors like metabolism, drug interactions, and individual variations in the drug's activation may influence its effectiveness.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 74 upvotes 5 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community Why is Kevin Mann (Haircafe) Hated?

in Chat 62 upvotes 1 year ago

Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.

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