134 citations
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August 2012 in “The Journal of Clinical Psychiatry” This study found that former finasteride users with persistent sexual side effects reported significantly higher rates of depressive symptoms and suicidal thoughts compared to controls.
6 citations
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January 2020 in “Dermatology” This study suggests that men under 40 who develop persistent sexual side effects and insomnia after using finasteride for alopecia may be at increased risk of suicide.
1 citations
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June 2025 in “European Journal of Clinical Pharmacology” In this study, researchers found a statistically significant increase in reports of suicidality and depression associated with finasteride use, especially in younger individuals, whereas dutasteride showed no significant signal for suicidality and a weaker signal for depression.
1 citations
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March 2023 in “Scientific Reports” This cohort study found no overall increased risk of suicidal behaviors with finasteride versus dutasteride in men aged 50 and older, but suggested potential risk for those with a history of mood disorders.
September 2025 in “Therapies” This study found that finasteride is associated with significant depressive effects, including an increased risk of suicidality, which can persist beyond 20 months after stopping the medication, even without prior sexual dysfunction or psychiatric history.