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In this study, chronic finasteride administration in male rats led to depression- and anxiety-like behaviors only in specific tests and moderately affected hippocampal synaptic plasticity, possibly due to adaptive plasma corticosterone level changes over time.

In this study, naringenin and its methylated derivatives reduced depression-like behaviors and inflammation markers in mice exposed to finasteride, suggesting their potential as effective and safe anti-depressive agents.

This study found that honokiol inhibits enzymes related to testosterone degradation in vitro, suggesting its potential as a lead compound for developing antiaging bioactive ingredients for men.

This study suggests that red ginseng rhizome extracts, particularly ginsenoside Ro, may promote hair re-growth in an androgenetic alopecia model due to their inhibitory activity on testosterone 5α-reductase.

This study found that Puerariae Flos extract inhibited testosterone 5α-reductase and promoted hair growth in mouse models, suggesting its potential use for treating androgenic alopecia.