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research Skin inflammation activates intestinal stromal fibroblasts and promotes colitis

37 citations , October 2021 in “Journal of Clinical Investigation”

This study suggests that inflammation in the skin can exacerbate intestinal inflammation in inflammatory bowel diseases by activating fibroblasts in the colon through hyaluronan fragments released during skin inflammation.

research Differentiation capacity of stromal fibroblast-like cells from human bone marrow, adipose tissue, hair follicle dermal papilla and derma

7 citations , February 2009 in “Cell and tissue biology”

research Conditioned Medium from Human Mesenchymal Stromal Cells: Towards the Clinical Translation

166 citations , April 2019 in “International Journal of Molecular Sciences”

The researchers reported that they predicted associations between certain components of MSC-conditioned medium and its ability to stimulate cell migration in vitro, identifying factors affecting its biological activity.

research RANKL Induces Organized Lymph Node Growth by Stromal Cell Proliferation

42 citations , December 2011 in “The journal of immunology/The Journal of immunology”

In this study, transgenic mice with Rank expression in hair follicles showed excessive lymph node growth, which could be normalized by neutralizing the overproduced RANKL, underscoring its role in immune system regulation.

research States and Fates of Skin Fibroblasts Revealed through Chromatin Accessibility

February 2022 in “Journal of Investigative Dermatology”

The researchers in this study found that neonatal mouse skin fibroblasts show distinct chromatin landscapes directing differentiation into dermal papilla or adipocyte lineages, and such plasticity may inform strategies for enhancing regenerative capacities in adult skin.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 7 upvotes 2 years ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.

5 upvotes 3 years ago

Fibrin-based hydrogels support stem cells for hair follicle regeneration, showing promise for treating alopecia and wound healing. They enhance cell viability, maintain stemness, and promote hair and tissue regeneration without teratoma formation.

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