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research Life Events Preceding Alopecia Areata Onset—a Descriptive Retrospective Cohort Study Focusing on Strain

January 2026 in “SHILAP Revista de lepidopterología”

This study observed that 82% of patients with alopecia areata reported experiencing at least one stressful life event prior to the onset of their condition, highlighting the significance of considering life event strain in managing these patients.

research Effects of non-ablative fractional erbium glass laser treatment on gene regulation in human three-dimensional skin models

24 citations , January 2016 in “Lasers in Medical Science”

This study found that non-ablative fractional erbium glass laser treatment affected gene regulation in human skin models by downregulating MMP and interleukin expression, suggesting potential roles in dermal remodeling and anti-inflammatory effects.

A Model for the Turnover of Dihydrotestosterone in the Presence of the Irreversible 5α-Reductase Inhibitors GI198745 and Finasteride

research A model for the turnover of dihydrotestosterone in the presence of the irreversible 5α-reductase inhibitors GI198745 and finasteride

60 citations , December 1998 in “Clinical Pharmacology & Therapeutics”

Both drugs lower DHT levels, with GI198745 being more effective.

research Integrated Model of Care for Polycystic Ovary Syndrome

10 citations , January 2018 in “Seminars in Reproductive Medicine”

This review discusses the challenges in diagnosing and managing polycystic ovary syndrome and highlights the need for an integrated, multidisciplinary healthcare model tailored to the diverse needs of women with PCOS; it reports no new clinical findings.

research A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease

67 citations , November 2019 in “Nature Communications”

This study demonstrated that a c-Kit-CreER-driven mouse model confirms melanocyte stem cells as a genuine source of melanoma, paralleling human melanoma in heterogeneity and gene signatures.

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community Do it yourself topical Fin and Min solution works

in Progress Pictures 119 upvotes 1 year ago

A homemade topical solution of finasteride and minoxidil effectively stopped hair shedding and promoted regrowth without side effects. Users shared experiences and discussed different concentrations and application methods.

community Making your own RT1640 in China

4 years ago

RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

community 4.5 month hair transformation with HOMEMADE topical solution. Saying bye to the Norwood reaper.

in Progress Pictures 128 upvotes 2 years ago

A user shared their 4.5-month hair transformation using a homemade topical solution with 5% minoxidil and crushed finasteride pills, applied twice daily with weekly microneedling. They plan to switch to once-daily application with tretinoin gel to enhance absorption.

community Article of all potential future cures

25 upvotes 1 year ago

Ritlecitinib and PP405 show promise for hair regrowth. Diagnosing the cause of hair loss is crucial before treatment.

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