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research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles

47 citations, December 2019 in “Frontiers in immunology”

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

research Characterization of Novel TMEM173 Mutation Causing a Lupus- and SAVI-Like Phenotype, Modified by Polymorphisms in TMEM173 and IFIH1

September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

A new mutation in the STING protein causes a disease with lupus-like symptoms and responds well to a specific inhibitor treatment.

research Characterization of Novel TMEM173 Mutation with Additive IFIH1 Risk Allele

1 citations, August 2018 in “bioRxiv (Cold Spring Harbor Laboratory)”

A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.

research A Rare Manifestation of STING-Associated Vasculopathy with Onset in Infancy: A Case Report

January 2024 in “Pediatric rheumatology online journal”

Early genetic testing and JAK inhibitors can help treat systemic inflammation in SAVI patients.

research Molecular Mechanisms of Viral Oncogenesis in Humans

141 citations, August 2018 in “Nature Reviews Microbiology”

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

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Community Join

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community CB-03-01 supposed hair loss cure

in Treatment 7 upvotes 3 years ago

The conversation discusses why CB-03-01, a potential hair loss treatment, isn't widely discussed despite evidence of its effectiveness and safety. Some users mention other treatments like melatonin, procianidin b2, and RU58841, debating their effectiveness and safety.

community 28 Days on Oral Min and Vitamins Only

in Is this regrowth? 132 upvotes 8 months ago

The user is taking 2.5mg of oral Minoxidil and using Rosemary and Peppermint oil for hair regrowth, with no side effects reported. They are considering increasing the dosage to 5mg after three months and have been advised to include a dermaroller in their routine.

community 7-month (fin/min/keto/micro) Progress [34M]

in Progress Pictures 538 upvotes 1 year ago

User shared 7-month progress of hair loss treatment, using daily 1mg Fin, 2x Min, monthly micro-needling, and ketocoz shampoo. They advise focusing on haircare, diet, and mental health after establishing a routine.

community Eliminating scalp itch leads to regrowth (and my RU58841 progress)

in Research/Science 61 upvotes 1 year ago

User experienced hair regrowth after eliminating scalp itch with RU58841. Others discussed itch and hair loss connection, and effectiveness of combining RU58841 with 5AR inhibitors.

community 4 Year Update (27M)(Fin+Min+Micro-needling)

in Progress Pictures 1778 upvotes 1 year ago

EDHARRINGTON's journey to regrow his hair using finasteride, topical minoxidil, and micro-needling treatments over 4 years, with others commenting their support and admiration for his results.

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