1 citations
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February 2022 in “Brain Research Bulletin” This study found that finasteride reduced impulsivity in a rat model of pramipexole-induced probability discounting, possibly by normalizing D3 receptor expression in the nucleus accumbens.
46 citations
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May 2012 in “Molecular and Cellular Endocrinology” In this study, higher expression levels of aromatase and steroidogenic acute regulatory protein were correlated with increased estrogen synthesis and fewer hair follicles in human skin, suggesting a link to elastic fiber formation and hair growth.
21 citations
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August 2001 in “PubMed” This article discusses the enzyme pathways involved in androgenetic alopecia and the role of finasteride in reducing dihydrotestosterone levels to promote hair growth; it reports no new clinical results.
September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that finasteride reduced opioid self-administration in zebrafish and rats without affecting pain relief, suggesting steroidogenic pathways may offer new treatment avenues for opioid use disorder.
April 2008 in “Annals of General Psychiatry” This study found that social isolation in rats enhanced the effects of ethanol on certain brain steroids, increased GABAA receptor subunits, and amplified ethanol's inhibitory effects on seizures.