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    Research 10 of 1000+

    1. GhDET2, a steroid 5α‐reductase, plays an important role in cotton fiber cell initiation and elongation The Plant Journal · 2007 · 193 citations
    2. Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP−Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor Journal of the American Chemical Society · 1996 · 136 citations
    3. Steroid 5α-reductases and 3α-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism 2001 · 115 citations
    4. Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders Current Pharmaceutical Design · 2011 · 72 citations
    5. Human Osteoblast-Like Cells Express Predominantly Steroid 5α-Reductase Type 1 The Journal of Clinical Endocrinology & Metabolism · 2002 · 56 citations
    6. LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1. Proceedings of the National Academy of Sciences of the United States of America · 1993 · 53 citations
    7. Inhibition of Human Steroid 5β-Reductase (AKR1D1) by Finasteride and Structure of the Enzyme-Inhibitor Complex Journal of Biological Chemistry · 2009 · 47 citations
    8. Sex dependent influence of a functional polymorphism in steroid 5‐α‐reductase type 2 (<i>SRD5A2</i>) on post‐traumatic stress symptoms American Journal of Medical Genetics Part B Neuropsychiatric Genetics · 2013 · 35 citations
    9. Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride Nature Communications · 2020 · 30 citations
    10. Differential expression of steroid 5α-reductase isozymes and association with disease severity and angiogenic genes predict their biological role in prostate cancer Endocrine Related Cancer · 2010 · 30 citations
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    Community 10 of 74

    1. How finasteride lowers brain's happiness steroid allopregnanolone and causes depression: systemic dihydroprogesterone crosses blood brain barrier, you don't even need finasteride and brain 5ar for that Reddit · 31 May 2025
    2. How to Keep Your Hair on Steroids Reddit · 10 Sept 2024
    3. “Dutasteride destroyed my hair” recently I noticed the same users Reddit · 30 Aug 2024
    4. Finasteride, dutasteride, and oral min- My experience Reddit · 19 Apr 2021
    5. How to know if shedding is from tren or minoxidil? Reddit · 29 Mar 2024
    6. Is DUT better or worse than FIN? Reddit · 22 Oct 2023
    7. "DHT Itch" and onset Seborrheic Dermatitis Reddit · 25 Sept 2023
    8. The truth about Dutasteride (w/ sources) Reddit · 24 Jan 2023
    9. Doctor says i shouldn't take fin because its "hormonal" Reddit · 9 Aug 2024
    10. I’ve been on oral finasteride/Proscar for 15 years. (AMA) Reddit · 12 Jul 2024
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    Learn 1 of 4

    1. Neem Oil Oil from the neem tree, used in traditional remedies
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