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This report presents a case where multiple steatocystomas appeared in a psoriatic patient during ustekinumab treatment, suggesting the drug may unmask a genetic predisposition to steatocystoma multiplex.

This review provides an overview of the etiology, presentation, and diagnosis of steatocystomas, including subtypes and complications, while detailing their history, epidemiology, and management strategies.

This study found that mutations in the K17 gene underlie both pachyonychia congenita type 2 and steatocystoma multiplex phenotypes, regardless of the specific mutation involved.

This study supports the idea that steatocystoma multiplex is a hamartomatous condition and suggests it may be a variant of eruptive vellus hair cyst, both originating in the pilosebaceous duct.

The authors concluded that milia, steatocystoma multiplex, and eruptive vellus hair cysts may be subtypes of multiple pilosebaceous cysts with overlapping histologic features.