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All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration

research All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration

January 2018 in “Stem cell biology and regenerative medicine”

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

research Metabolic Pathways of Eicosanoids: Derivatives of Arachidonic Acid and Their Significance in Skin

January 2025 in “Cellular & Molecular Biology Letters”

Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.

research Developmental Genetics of Color Pattern Establishment in Cats

20 citations , September 2021 in “Nature communications”

Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.

research Microbiome in the Hair Follicle of Androgenetic Alopecia Patients

26 citations , May 2019 in “PLOS ONE”

Hair loss patients have different microbes in hair follicles, possibly affecting hair loss.

Immunological Aspects and Gender Bias During Respiratory Viral Infections Including Novel Coronavirus Disease-19 (COVID-19): A Scoping Review

research Immunological Aspects and Gender Bias During Respiratory Viral Infections Including Novel Coronavirus Disease-19 (COVID-19): A Scoping Review

11 citations , May 2021 in “Journal of Medical Virology”

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

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Community Join

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community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

in Research/Science 126 upvotes 1 year ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community Results on 2 months of Dutasteride 0.5mg + 2.5mg Minoxidil

in Progress Pictures 147 upvotes 2 years ago

A user's results after two months of using Dutasteride and Minoxidil, alongside other treatments such as multivitamins, derma rolling, finasteride, topical minoxidil, Nizoral shampoo, Pyrithione zinc shampoo, hair vitamins, and rosemary oil. People in the conversation shared encouragement and discussed their own regimens for treating hair loss.

community (25M) 25 days of treatment min + microneedling

in Progress Pictures 173 upvotes 1 year ago

A user shared progress pictures after 25 days of using Minoxidil, microneedling, and recently started topical finasteride for hair loss. Some commenters are skeptical about the results, while others notice new hair growth.

community 20M NW5 1 month progress on oral finasteride 1mg and 3mg oral minoxidil

in Is this regrowth? 9 upvotes 6 months ago

A 20-year-old is experiencing aggressive hair loss and is using oral finasteride, oral minoxidil, red light therapy, and considering adding dutasteride. Users advise patience, consistency, and waiting 3-6 months for potential regrowth.

community only microneedling and supplements

in Progress Pictures 67 upvotes 2 months ago

The user used microneedling, zinc, vitamin D3, biotin, magnesium, saw palmetto, pumpkin seed oil, and a DHT-blocker shampoo with biotin for hair loss. They are considering adding minoxidil due to stagnation in progress.

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