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research Context-Dependent Effect of sPLA2-IIA Induced Proliferation on Murine Hair Follicle Stem Cells and Human Epithelial Cancer

13 citations , September 2019 in “EBioMedicine”

sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.

research sPLA2-IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation

9 citations , June 2016 in “Stem cells”

Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

research Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin

35 citations , January 2011 in “Journal of Biological Chemistry”

sPLA2-X is crucial for normal hair growth and follicle health.

research Expression and Function of Group IIE Phospholipase A2 in Mouse Skin

26 citations , May 2016 in “Journal of biological chemistry/The Journal of biological chemistry”

sPLA2-IIE is crucial for normal hair follicle structure and skin health.

research Group IID, IIE, IIF, and III Secreted Phospholipase A2s

23 citations , August 2018 in “Biochimica and biophysica acta. Molecular and cell biology of lipids”

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

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Community Join

5 / 30 results

community Trinov seems to be working.

20 upvotes 6 years ago

Minoxidil initially worked but then failed. Trinov has significantly reduced shedding and shows promising results.

community Keratin fibers vs. Gossypium Herbaceum Hair fibers

in Product 1 upvotes 1 year ago

The conversation is about comparing keratin hair fibers to Gossypium Herbaceum hair fibers for diffuse hair loss. The user prefers keratin fibers for their durability and is seeking a bulk purchase option.

community Megadosing Koshine826(Pyrilutamide), my Plan.

in Treatment 1 upvotes 1 year ago

The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.

community Is it possible to get an HT without scarring? (when you’re fully shaved)

in Chat 12 upvotes 2 years ago

User is 25, using oral finasteride for 4 years, topical minoxidil for 3 years, and microneedling. They ask if hair transplant can be done without scarring when shaving head completely bald later.

community MicroRNA can regrow 90% of lost hair, researchers find

in Treatment 502 upvotes 3 years ago

Researchers finding that microRNA can potentially regrow 90% of lost hair, and the challenges involved in moving this research forward to human trials. Various treatments for hair loss, such as finasteride and minoxidil, have been discussed.

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