research Coinfection of Secondary Syphilis, Condyloma Acuminata, and Human Immunodeficiency Virus (HIV) in a Homosexual Man
A 22-year-old homosexual man presented with symptoms including red scaly patches, hair loss, and genital lumps, leading to a diagnosis of coinfection with secondary syphilis, condyloma acuminata, and HIV. Examination revealed nonscarring alopecia, erythematous plaques, and verrucous lesions. Tests showed a CD4 count of 112 cells/µl, reactive VDRL/RPR at 1:256, and TPHA at >1:5,120. Histopathology confirmed skin syphilis and condyloma acuminata, with immunohistochemistry showing Spirochaeta. The case highlights the increased risk of STIs in MSM, particularly the coexistence of HPV and HIV, which facilitate syphilis infection.
