research Synaptic Relationships Between Hair Follicle Afferents and Neurons Expressing GABA and Glycine-Like Immunoreactivity in the Spinal Cord of the Rat
Glycine likely affects dendrites connected to hair follicle terminals in rats.
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5 / 1000+ resultsresearch Spinal Bicuculline Produces Hypersensitivity of Dorsal Horn Neurons: Effects of Excitatory Amino Acid Antagonists
Blocking GABA(A) receptors increases neuron sensitivity, showing GABA and glycine have different roles in pain.
research Neuronal Model of Tactile Allodynia Produced by Spinal Strychnine: Effects of Excitatory Amino Acid Receptor Antagonists and a Mu-Opiate Receptor Agonist
Disruption of glycinergic circuits increases pain sensitivity, suggesting new pain treatment options.
research Stem Cell-Derived Motor Neurons from Spinal and Bulbar Muscular Atrophy Patients
The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.
research Molecular Mechanisms of Type II Spiral Ganglion Neuron Development
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5 / 68 resultscommunity Finasteride - impact on Neurosteroids, which yes, \are important and not a garbage hormone
Finasteride may affect neurosteroids, impacting mood and sexual function, with varied user experiences. Some report side effects like depression and sexual dysfunction, while others find it effective for hair retention or prefer alternatives like Dutasteride or topical treatments.
community What is the real impact of dutasteride on neurosteroids? A little review of 2 scientific datas
Dutasteride at 0.5 mg/day does not significantly alter allopregnanolone levels, but higher doses (2.5 mg/day) do. Dutasteride may also have anti-neuroinflammatory effects, but the impact on neurosteroids is still debated.
community A systematic bro-science review of DHT, 5AR, neurosteroids, sexual health and 5AR inhibitors
Hair loss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.
community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.
Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.
community Hair loss research focused on chemistry for decades because we misunderstood the mechanics of growth.
Hair growth relies on mechanical forces, not just chemicals, with tissue acting like a motor. Minoxidil and finasteride help, but maintaining tissue elasticity and addressing mechanical issues are essential.