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Sphere Formation Increases the Ability of Cultured Human Dermal Papilla Cells to Induce Hair Follicles from Mouse Epidermal Cells in a Reconstitution Assay

research Sphere Formation Increases the Ability of Cultured Human Dermal Papilla Cells to Induce Hair Follicles from Mouse Epidermal Cells in a Reconstitution Assay

75 citations , August 2011 in “Journal of Investigative Dermatology”

Forming spheres boosts the ability of certain human cells to create hair follicles when mixed with mouse skin cells.

Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences Between Sox2-Positive and Sox2-Negative Cells In Vitro and In Vivo

research Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences Between Sox2-Positive and Sox2-Negative Cells In Vitro and In Vivo

68 citations , December 2011 in “Journal of Investigative Dermatology”

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

research Characterization of Human Dermal Papilla Cells in Alginate Spheres

8 citations , October 2018 in “Applied sciences”

Alginate spheres help maintain hair growth potential in human cells for hair loss treatment.

research Ablation of Alkaline Phosphatase in Human Dermal Papilla Spheroid Impairs Hair Follicle Induction

April 2016 in “Journal of Investigative Dermatology”

Removing alkaline phosphatase from human skin cells hinders the creation of new hair follicles.

Establishment and Characterization of Matched Immortalized Human Frontal and Occipital Scalp Dermal Papilla Cell Lines from Androgenetic Alopecia

research Establishment and Characterization of Matched Immortalized Human Frontal and Occipital Scalp Dermal Papilla Cell Lines from Androgenetic Alopecia

December 2023 in “Scientific Reports”

Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.

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Community Join

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community Getting a haircut feels like a humiliation ritual when losing hair

in Styling 209 upvotes 1 month ago

Many people feel self-conscious about hair loss during haircuts, with some using treatments like finasteride and minoxidil. Others cope by cutting their own hair or finding a trusted barber to manage thinning areas.

community Male pattern baldness is not cosmetic.

in Chat 213 upvotes 1 week ago

Male pattern baldness is linked to health risks and should be treated medically. Finasteride is effective and should be insurance-covered.

community Federal Grant Cuts have impacted PP405 related research

in Technology 458 upvotes 3 months ago

Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.

community People treat you way nicer when you have hair, I didn’t believe it until it happened to me

in Chat 370 upvotes 3 months ago

Having hair improves social interactions and treatment by others, with hair transplants and finasteride enhancing confidence and attractiveness. People often receive more positive attention after addressing hair loss.

community Had a rough week. What to do now?

in Treatment 36 upvotes 1 year ago

The user had a rough week after being told they couldn't get a hair transplant due to insufficient donor area and worsening balding. They were advised to increase their oral Minoxidil dosage and consider switching from Finasteride to Dutasteride.

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