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Sphere Formation Increases the Ability of Cultured Human Dermal Papilla Cells to Induce Hair Follicles from Mouse Epidermal Cells in a Reconstitution Assay

research Sphere Formation Increases the Ability of Cultured Human Dermal Papilla Cells to Induce Hair Follicles from Mouse Epidermal Cells in a Reconstitution Assay

75 citations, August 2011 in “Journal of Investigative Dermatology”

Forming spheres boosts the ability of certain human cells to create hair follicles when mixed with mouse skin cells.

Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences Between Sox2-Positive and Sox2-Negative Cells In Vitro and In Vivo

research Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences Between Sox2-Positive and Sox2-Negative Cells In Vitro and In Vivo

68 citations, December 2011 in “Journal of Investigative Dermatology”

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

research Characterization of Human Dermal Papilla Cells in Alginate Spheres

8 citations, October 2018 in “Applied sciences”

Alginate spheres help maintain hair growth potential in human cells for hair loss treatment.

research Ablation of Alkaline Phosphatase in Human Dermal Papilla Spheroid Impairs Hair Follicle Induction

April 2016 in “Journal of Investigative Dermatology”

Removing alkaline phosphatase from human skin cells hinders the creation of new hair follicles.

Establishment and Characterization of Matched Immortalized Human Frontal and Occipital Scalp Dermal Papilla Cell Lines from Androgenetic Alopecia

research Establishment and Characterization of Matched Immortalized Human Frontal and Occipital Scalp Dermal Papilla Cell Lines from Androgenetic Alopecia

December 2023 in “Scientific Reports”

Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.

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Community Join

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community Had a rough week. What to do now?

in Treatment 36 upvotes 3 months ago

The user had a rough week after being told they couldn't get a hair transplant due to insufficient donor area and worsening balding. They were advised to increase their oral Minoxidil dosage and consider switching from Finasteride to Dutasteride.

community Quick word of advice for you guys wondering if you're balding

in Chat 160 upvotes 1 year ago

User noticed scalp showing at 26, started finasteride at 28, and saw hair improvement by 30. Others shared similar experiences and advised trusting personal observations and trying finasteride early to prevent further hair loss.

community Finally decided to buzz my head after experiencing hair loss since I was 17 (23 now). I think it looks decent, swipe to see what I was rocking before during the pandemic. Who knows maybe I’ll hop on fin but as someone who struggles with chronic fatigue and low test I’m hesitant.

in Shaved/buzzed 326 upvotes 2 years ago

A user's decision to shave their head after experiencing hair loss since the age of 17, and discussion around the potential use of Fin for treating hair loss.

community New potential hair loss treatment (news release)

in Treatment 186 upvotes 4 years ago

New potential hair loss treatment uses molecules from hairy moles to stimulate follicle growth. Topical solution requires less frequent application, like Botox injections a few times per year.

community Keratin microspheres - breakthrough

in Research/Science 13 upvotes 8 months ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

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