June 2024 in “Georgetown medical review” This article evaluated evidence on finasteride's effects on male reproductive health, finding contradictory data about its adverse effects, but consensus that such cases are infrequent in research and clinical settings.
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February 2024 in “Pharmacognosy Journal” In this study, fenugreek seed extract showed significant androgenic and spermatogenic effects in male rats, likely through inhibiting testosterone metabolism, without impacting cardiovascular health.
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June 2018 in “Current Urology Reports” This review suggests that while finasteride for male pattern hair loss was previously considered safe, there is now evidence associating 5-α reductase inhibitors with significant sexual and reproductive side effects.
January 1930 in “Experimental Biology and Medicine” This study found that high voltage cathode rays caused significant damage to the spermiogenic epithelium of male adult white rats, showing particular sensitivity of germinal epithelium to radiation.
June 2018 in “The Journal of Sexual Medicine” In this study, finasteride was found to significantly reduce DHT levels and affect spermatogenic markers in rats, while DA-9401 co-treatment indicated potential ameliorative effects.
