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Single-Cell Transcriptomic Analysis of Small and Large Wounds Reveals the Distinct Spatial Organization of Regenerative Fibroblasts

research Single-Cell Transcriptomic Analysis of Small and Large Wounds Reveals the Distinct Spatial Organization of Regenerative Fibroblasts

35 citations, November 2020 in “Experimental Dermatology”

Different types of skin cells are organized in a special way in large wounds to help with healing and hair growth.

Efficient Generation of Skin Organoids from Pluripotent Cells Using Defined Extracellular Matrix Cues and Morphogen Gradients in a Microfluidic Device

research Efficient Generation of Skin Organoids from Pluripotent Cells Using Defined Extracellular Matrix Cues and Morphogen Gradients in a Microfluidic Device

March 2024 in “Advanced healthcare materials/Advanced Healthcare Materials”

Scientists developed a new way to create skin-like structures from stem cells using a special 3D gel and a device that improves cell organization and increases hair growth.

research Sostdc1 Defines the Size and Number of Skin Appendage Placodes

56 citations, February 2012 in “Developmental biology”

Sostdc1 controls the size and number of hair and mammary gland structures.

All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration

research All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration

January 2018 in “Stem cell biology and regenerative medicine”

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

research Compartmentalized Organization: A Common and Required Feature of Stem Cell Niches?

63 citations, April 2010 in “Development”

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

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community Kintor has announced the results for their human Phase I trials of GT20029

in Research/Science 253 upvotes 2 years ago

The conversation discusses the potential of a new hair loss treatment, GT20029, which may prevent hair loss by destroying androgen receptors on the scalp. Users express hope for the treatment's success and speculate on its usage routine, effectiveness, and possible side effects.