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GlossaryAlopecia (Sparse Hair Growth)

refers to hair loss from areas where hair normally grows

Alopecia refers to the partial or complete loss of hair from areas of the body where it typically grows, most commonly the scalp. It can be caused by a variety of factors including genetics, autoimmune disorders, hormonal changes, and environmental influences. There are different types of alopecia, such as alopecia areata, which is an autoimmune condition where the immune system attacks hair follicles, leading to patchy hair loss.

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research The G60S Connexin43 Mutant Regulates Hair Growth and Hair Fiber Morphology in a Mouse Model of Human Oculodentodigital Dysplasia

17 citations, June 2011 in “The journal of investigative dermatology/Journal of investigative dermatology”

The G60S Connexin43 mutation causes hair growth issues and poor hair quality in mice, similar to human ODDD patients.

research Marie-Unna Hereditary Hypotrichosis: Case Report and Review of the Literature

November 2011 in “Pediatric dermatology”

Marie-Unna Hereditary Hypotrichosis is a rare genetic condition causing sparse hair growth, requiring specific recognition for proper care.

research Premature Termination of Hair Follicle Morphogenesis and Accelerated Hair Follicle Cycling in Iasi Congenital Atrichia (fzica) Mice Points to Fuzzy as a Key Element of Hair Cycle Control

20 citations, July 2005 in “Experimental dermatology”

The fuzzy gene is crucial for controlling hair growth cycles.

research Roles of MED1 in Quiescence of Hair Follicle Stem Cells and Maintenance of Normal Hair Cycling

16 citations, August 2012 in “The journal of investigative dermatology/Journal of investigative dermatology”

MED1 is essential for normal hair growth and maintaining hair follicle stem cells.

research The Role of P-Cadherin in Skin Biology and Pathology: Lessons from the Hair Follicle

15 citations, February 2015 in “Cell & tissue research/Cell and tissue research”

P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.

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community TWIST-1 and the cure: Is it really that easy?

in Research/Science 283 upvotes 2 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

community 5 Months Hair Transplant Progress / 3500 Grafts

in Transplants 1662 upvotes 1 year ago

A user shared their positive experience with a hair transplant of 3500 grafts, showing significant improvement in appearance after 5 months. They underwent the procedure at Heva Clinic in Istanbul for $2,300 USD, which included aftercare, and attributed their hair loss to both genetics and traction alopecia from tight hairstyles.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community 24M , been a month on minoxidil Finastride nizoral any difference ?

in Treatment 153 upvotes 2 years ago

A user who has been taking minoxidil, finasteride and nizoral for one month, asking if there is any difference in their hair loss; the responses suggest that some improvement may have been seen but it can be hard to tell with just one month of treatment.

community I know that wanting a cure is unrealistic and too much to ask. But I at least want medicine that will work reliably for almost everyone.

in Chat 51 upvotes 3 months ago

The conversation is about the effectiveness of hair loss treatments like finasteride, dutasteride, and minoxidil. Users agree these treatments help maintain hair but don't guarantee miraculous regrowth, emphasizing early intervention for best results.

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