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research 329 Mechanisms of Cutaneous Adverse Events during Targeted Cancer Therapy

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study explores how EGFR signaling impacts skin inflammation and follicular integrity during hair eruption, aiming to identify druggable pathways to mitigate skin inflammation in cancer patients receiving EGFR inhibitors.

research Discovery of genes and proteins possibly regulating mean wool fibre diameter using cDNA microarray and proteomic approaches

6 citations , May 2020 in “Scientific reports”

In this study, microarray and proteomic analyses indicated that genes involved in immune response, receptor binding, and growth factor activity might influence wool fibre diameter in sheep.

research De novo designed bifunctional proteins for targeted protein degradation

December 2025

In this study, researchers developed de novo designed hetero-bifunctional proteins as an alternative approach for targeted protein degradation, successfully targeting BCL-xL for degradation in cells and inducing apoptosis, which may expand the range of addressable E3 ligases and disease targets.

research A molecular wound response program associated with regeneration initiation in planarians

212 citations , May 2012 in “Genes & Development”

This study identified a set of wound-induced genes in planarians that play a role in regeneration initiation, with some genes specifically activating within regenerative cells called neoblasts.

Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis

research Transforming growth factor-β in stem cells and tissue homeostasis

245 citations , January 2018 in “Bone Research”

This review discusses the role of TGF-β signaling in stem cell recruitment and tissue regeneration, indicating that abnormalities in TGF-β activation contribute to various major diseases and suggesting avenues for therapeutic intervention.

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community Scalp testosterone does NOT cause hair loss, what is this baseless claim ?

in Research/Science 13 upvotes 5 months ago

DHT, not testosterone, causes hair loss. Treatments like finasteride, dutasteride, and RU58841 target DHT to manage hair loss.

community SOS – The cure for women = PREGNANCY

2 upvotes 7 months ago

Pregnancy can temporarily reverse hair loss in women, but attempts to mimic pregnancy hormones with treatments like contraceptive pills, spironolactone, estradiol, progesterone, finasteride, and minoxidil have been ineffective. The discussion highlights the need for research into the hormonal mechanisms of pregnancy that affect hair regrowth.

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