May 2026 in “Journal of Photochemistry and Photobiology” This review found that solar radiation, pollution, and trace metals cause significant damage to human hair, with factors like UVB radiation primarily affecting light-colored and bleached hair; most data were derived from in vitro and ex vivo simulations.
May 2026 in “International Journal of Cosmetic Science” This study found that UV radiation exposure during a simulated Brazilian summer caused more significant mechanical damage to natural hair than bleaching, although both caused comparable structural alterations, with double bleaching leading to the most severe protein degradation.
January 2025 in “Journal of Bioresource Management” This study found that inhibiting the ATR kinase with VE-822 impairs DNA repair capability in quiescent human keratinocytes exposed to solar-simulated UV radiation, suggesting ATR's critical role in facilitating effective DNA damage repair and cellular recovery under UV stress conditions.
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January 2005 in “Endocrine journal” This article discusses the potential role of melatonin in protecting skin against stress and maintaining homeostasis, based on its local synthesis and various protective functions, but presents no new clinical results.
November 2020 in “Journal of The American Academy of Dermatology” This study investigated the use of spironolactone in patients with estrogen-dependent cancers, aiming to determine if it is linked to increased cancer recurrence risk, but results are not reported.