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Updated Skin Transcriptomic Atlas Depicted by Reciprocal Contribution of Single-Nucleus RNA Sequencing and Single-Cell RNA Sequencing

research Updated Skin Transcriptomic Atlas Depicted by Reciprocal Contribution of Single-Nucleus RNA Sequencing and Single-Cell RNA Sequencing

April 2023 in “Journal of Investigative Dermatology”

The research updated the skin cell profile, finding new skin cell markers and showing fibroblasts' key role in skin health.

research Single-Cell Sequencing Technology in Ruminant Livestock: Challenges and Opportunities

5 citations , May 2024 in “Current Issues in Molecular Biology”

Single-cell sequencing can improve livestock health and productivity but faces challenges in precise cell analysis.

Single-Nucleus and Bulk RNA Sequencing Reveals the Involvement of Natural Killer and CD8+ T Cells in the Progression of Androgenetic Alopecia

research Single-Nucleus and Bulk RNA Sequencing Reveals the Involvement of Natural Killer and CD8+ T Cells in the Progression of Androgenetic Alopecia

May 2025 in “Journal of Inflammation Research”

Natural killer and CD8+ T cells play a key role in hair loss in androgenetic alopecia.

research From Bedside to Bench: Regulation of Host Factors in SARS-CoV-2 Infection

4 citations , April 2021 in “Experimental and Molecular Medicine”

The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.

research Exome-Wide Age-Of-Onset Analysis Reveals Exonic Variants In ERN1 And SPPL2C Associated With Alzheimer’s Disease

12 citations , February 2021 in “Translational Psychiatry”

Researchers found two new genetic variants linked to Alzheimer's disease.

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community My Theory Of Androgenic Alopecia

in Research/Science 17 upvotes 3 weeks ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community Concerns about CosmeRNA safety mechanisms

in Treatment 3 upvotes 2 years ago

Concerns about CosmeRNA safety mechanisms and potential side effects. Discussion includes comparisons to Fluridil and questions about nanoparticle specificity and siRNA stability.

community Since there is so much hype for cosmeRNA and HMI-115...

in Chat 49 upvotes 2 years ago

Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.

community Sandalore: a scientific homemade approch

19 upvotes 7 years ago

The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.

community What new hair-loss treatments actually look exciting right now (Oct 2025)

in Research/Science 171 upvotes 2 months ago

New hair loss treatments include Breezula, PP405, ET-02, KX-826, GT20029, VDPHL01, and CosmeRNA, with some showing promise in reactivating stem cells and reversing greying. Breezula and VDPHL01 are highlighted as potential add-ons or alternatives to current treatments like finasteride and minoxidil.

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