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Updated Skin Transcriptomic Atlas Depicted by Reciprocal Contribution of Single-Nucleus RNA Sequencing and Single-Cell RNA Sequencing

research Updated Skin Transcriptomic Atlas Depicted by Reciprocal Contribution of Single-Nucleus RNA Sequencing and Single-Cell RNA Sequencing

April 2023 in “Journal of Investigative Dermatology”

The research updated the skin cell profile, finding new skin cell markers and showing fibroblasts' key role in skin health.

research From Bedside to Bench: Regulation of Host Factors in SARS-CoV-2 Infection

4 citations, April 2021 in “Experimental and Molecular Medicine”

The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.

research Exome-Wide Age-Of-Onset Analysis Reveals Exonic Variants In ERN1 And SPPL2C Associated With Alzheimer’s Disease

12 citations, February 2021 in “Translational Psychiatry”

Researchers found two new genetic variants linked to Alzheimer's disease.

research A Transient Dermal Niche and Dual Epidermal Programs Underlie Sweat Gland Development

April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Sweat gland development involves two unique skin cell programs and a temporary skin environment.

research The Developmental Basis of Fingerprint Pattern Formation and Variation

44 citations, February 2023 in “Cell”

Fingerprints form uniquely before birth due to specific genetic pathways and local signals.

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community Concerns about CosmeRNA safety mechanisms

in Treatment 3 upvotes 1 year ago

Concerns about CosmeRNA safety mechanisms and potential side effects. Discussion includes comparisons to Fluridil and questions about nanoparticle specificity and siRNA stability.

community Since there is so much hype for cosmeRNA and HMI-115...

in Chat 47 upvotes 1 year ago

Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.

community Sandalore: a scientific homemade approch

20 upvotes 6 years ago

The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.

community cosmeRNA finally now it's pyrilutamide turn

in Chat 49 upvotes 1 year ago

Hair loss treatments discussed include cosmeRNA, minoxidil, finasteride, RU58841, and pyrilutamide. Users debate effectiveness, side effects, and upcoming treatments, with some expressing skepticism and others optimism.

community Anyone excited for CosmeRNA coming this month?

in Product 171 upvotes 1 year ago

CosmeRNA, a new hair loss treatment, is expected to release soon and may become part of the "big three" treatments alongside finasteride and minoxidil. It works differently from finasteride by targeting androgen receptors in hair follicles, potentially offering fewer side effects.

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