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      learn Microneedling

      technique to create small wounds in skin to activate collagen production and hair growth

      learn Mesotherapy

      technique to inject very small amounts of beneficial chemicals into the scalp

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles
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      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn Saw Palmetto

      a natural and far less effective alternative to Finasteride

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      community The link between hair loss and gut health

      in Research/Science  59 upvotes 4 years ago
      The conversation discusses the potential link between gut health and hair loss, with personal experiences of hair thinning and stomach issues shared. Some individuals found no success with common hair loss treatments like Minoxidil and Finasteride and are exploring the impact of gut health on hair growth.

      community Methods Of Staying Safe On Ru58841 - My 2 Cents

      in Research/Science  9 upvotes 1 week ago
      RU58841 is used topically to prevent hair loss by blocking DHT, with suggestions to drink grapefruit juice, take breaks, avoid microneedling, and use lower concentrations to reduce side effects. Users discuss applying it at night to minimize systemic absorption.
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      community Lost density 60% all over scalp in 120 days (4months)

      in Update  10 upvotes 7 months ago
      A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2452 upvotes 3 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.