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research Canonical Prolactin Signaling and Global mRNA Expression in the Skin of Holstein Heifers Carrying the SLICK1 Allele of the Prolactin Receptor Gene

1 citations , February 2025 in “Journal of Dairy Science”

The SLICK1 allele in Holstein heifers affects hair and immune traits without altering prolactin signaling.

research Genetic Architecture of Thermotolerance Traits in Beef Cattle: A Novel Integration of SNP and Breed-of-Origin Effects

April 2025 in “Frontiers in Genetics”

Combining genetic models helps improve heat tolerance in beef cattle.

Use of Genetics in the Prediction of Success in Male Pattern Hair Loss Therapy and Mechanistic Studies

research Use of Genetics in the Prediction of Success in Male Pattern Hair Loss Therapy and Mechanistic Studies

February 2026 in “Frontiers in Pharmacology”

Genetics can help tailor treatments for male pattern hair loss, improving outcomes like stabilization or modest regrowth.

The Slick Hair Coat Locus Maps to Chromosome 20 in Senepol-Derived Cattle

research The Slick Hair Coat Locus Maps to Chromosome 20 in Senepol-Derived Cattle

51 citations , January 2007 in “Animal Genetics”

The gene for slick hair in Senepol cattle is located on chromosome 20 and may involve the SRD5A2 gene.

research Effects of the Bovine Slick Mutation on Heat Stress Responses and Hair Growth in Mice

January 2020

The mutation helps mice handle heat better without affecting hair growth.

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Community Join

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community 2 years after using finasteride

in Update 1203 upvotes 3 years ago

A user's two-year journey of using finasteride and minoxidil to treat hair loss, with other users providing advice, tips, and encouragement.

community Quote from Pelage (PP-405) Spokesperson...

in Research/Science 120 upvotes 4 months ago

Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

community “I’ll be happy as soon as fin brings my hair back” march 21, 2023

in Chat 138 upvotes 11 months ago

The user is struggling with hair loss and has tried treatments like finasteride, minoxidil, and dutasteride without success, considering a hair transplant as a future option. Others suggest focusing on mental health and self-worth beyond physical appearance, while some share their own experiences with similar treatments and outcomes.

community PP405 Phase 2a press release with early results

in Research/Science 700 upvotes 8 months ago

PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.

community 2022 Official beginner guide for "I'm losing my hair, what can I do?"

in STARTER GUIDE 686 upvotes 3 years ago

Hair loss treatments include Finasteride, Minoxidil, Ketoconazole shampoo, and Microneedling. Additional options are Dutasteride, oral Minoxidil, and hair transplants.

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