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      research Hair Follicle Stem Cell SLC3A2 Regulates Epithelial Regenerative Properties

      September 2025 in “Journal of Investigative Dermatology”
      This research found that deleting the SLC3A2 gene in hair follicle stem cells disrupts their maintenance and proper differentiation, leading to hair follicle growth defects and altered skin regeneration through a YAP/Taz-dependent pathway.

      research CD98hc (SLC3A2) regulation of skin homeostasis wanes with age

      35 citations , January 2013 in “˜The œJournal of experimental medicine/˜The œjournal of experimental medicine”
      This study found that deleting the CD98hc protein in mouse skin impairs wound healing and homeostasis, resembling aging effects, due to disrupted integrin signaling pathways.

      research Fibronectin meshwork controls epithelial stem cell fate

      2 citations , May 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”
      This study found that fibronectin is crucial for hair follicle stem cell function and regeneration, with its deletion impairing regeneration but restoration by dermal injection of exogenous fibronectin.

      research Symptomatic zinc deficiency in a full-term breast-fed infant

      20 citations , June 2010 in “Dermatology Online Journal”
      This report describes a case of hypozincemia type-II in an exclusively breast-fed infant, which resolved with zinc therapy and weaning, highlighting genetic factors in zinc transporter gene SLC30A2.

      research 1385 Characterizing the expression of metabolic markers in alopecia areata

      April 2023 in “˜The œjournal of investigative dermatology/Journal of investigative dermatology”
      This preliminary study of Alopecia Areata identified limited expression of certain metabolic transporters and enzymes in hair follicle immune cells, providing early insight into their unique energy needs.