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research Jagged-1+ Skin Tregs Modulate the Innate Immune Response to Wound Healing

June 2024 in “Research Square (Research Square)”

This study demonstrated that in mice, the absence of Jagged-1 expression in skin-resident regulatory T cells significantly delays wound healing by reducing the accumulation of neutrophils, highlighting the role of Jagged-1 in coordinating immune cell recruitment during injury.

research Regulatory T cells in autoimmune skin diseases

24 citations , March 2018 in “Experimental Dermatology”

This review explores the role of regulatory T cells in autoimmune skin disorders like alopecia areata and vitiligo, emphasizing unanswered questions and reporting no new experimental results.

research Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation

18 citations , November 2020 in “Frontiers in Cell and Developmental Biology”

This review discusses how inflammation influences hair follicle stem cell activities like wound healing and follicle cycling and suggests a potential link between inflammation, stem cell activation, and programmed cell death.

research Tissue Resident Foxp3+ Regulatory T Cells: Sentinels and Saboteurs in Health and Disease

9 citations , March 2022 in “Frontiers in Immunology”

This review discusses the roles and mechanisms of tissue-resident regulatory T cells in immune regulation and tissue homeostasis, but reports no new experimental results.

research Editors' Picks

August 2017 in “Journal of Investigative Dermatology”

Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.

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Community Join

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community 12 Months post FUE surgery hair result. 4052 grafts, 10130 hairs transplanted

686 upvotes 1 year ago

A user shared their positive experience 12 months after a hair transplant with 4052 grafts and 10130 hairs, using finasteride, red light therapy, B12, biotin, and rosemary oil. They are satisfied with the results and recommend these treatments.

community Jxl069 (pp405 api) week 8 update

205 upvotes 1 year ago

The user shared minimal results from using JXL-069 for hair loss, noting a slight lengthening of vellus hairs and plans to switch to a prodrug variant due to limited effectiveness. They also mentioned using finasteride and minoxidil, which have plateaued in results.

community Recent Study finds Laser caps are more effective than 5% minoxidil for AGA

in Research/Science 124 upvotes 2 years ago

Laser caps are found to be more effective than 5% minoxidil for treating hair loss, and when combined with minoxidil, they are even more effective. Some users report positive results with laser treatments, while others see no change; the devices are FDA approved, but opinions on their efficacy vary.

community Another molecular pathway to promote scarless healing and regenerate hair follicles

14 upvotes 8 months ago

Carnosic acid in rosemary extract may enhance skin repair and promote hair follicle regeneration. It could be used alone or with verteporfin for scarless healing after dermal wounding.

community My Idea for a possible new hairloss treatment

53 upvotes 6 years ago

Exploring a potential hair loss treatment using the enzyme AKR1C2 to locally reduce DHT levels. Challenges include enzyme delivery through the skin and high production costs, with gene therapy or stem cells suggested as future alternatives.

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Clinics

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SMP Specialist
Noelle Skin
Nice, France

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Noelle Skin