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Research

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research C/EBPα and C/EBPβ Are Required for Sebocyte Differentiation and Stratified Squamous Differentiation in Adult Mouse Skin

48 citations , March 2010 in “PloS one”

This study found that the co-ablation of C/EBPalpha and C/EBPbeta in adult mouse skin disrupted sebocyte differentiation and epidermal homeostasis, highlighting their critical roles in these processes.

Selective Ablation of Ctip2/Bcl11b in Epidermal Keratinocytes Triggers Atopic Dermatitis-Like Skin Inflammatory Responses in Adult Mice

research Selective Ablation of Ctip2/Bcl11b in Epidermal Keratinocytes Triggers Atopic Dermatitis-Like Skin Inflammatory Responses in Adult Mice

40 citations , December 2012 in “PLoS ONE”

This study found that selective deletion of Ctip2 in epidermal keratinocytes in adult mice leads to atopic dermatitis-like inflammation and suggests Ctip2 plays a crucial role in skin barrier maintenance and inflammatory regulation.

research Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System

142 citations , March 2019 in “Molecules/Molecules online/Molecules annual”

This review discusses the role of the endocannabinoid system in skin health and disease, highlighting its potential for future research and applications, but reports no new experimental results.

Chromatin Architectural Protein CTCF Controls Epidermal Barrier Formation, Hair Follicle Fate Maintenance, and Suppresses Inflammatory Responses in the Skin Epithelium

research 874 Chromatin architectural protein CTCF controls epidermal barrier formation, hair follicle fate maintenance and suppresses inflammatory responses in the skin epithelium

April 2017 in “Journal of Investigative Dermatology”

In this study, CTCF was found to play essential roles in epidermal differentiation and skin barrier formation, simultaneously acting as a suppressor of epithelial inflammatory responses in mouse skin.

research Expression of COUP-TF-interacting protein 2 (CTIP2) in mouse skin during development and in adulthood

33 citations , June 2007 in “Gene Expression Patterns”

This study found that CTIP2 is highly expressed in mouse skin during embryogenesis and adulthood, suggesting it may play a role in skin development and homeostasis.

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Community Join

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community Alternatives if can't tolerate minoxidil?

4 upvotes 3 weeks ago

The user is experiencing side effects from oral minoxidil and is considering switching to a topical solution or reducing the dose. They are also using dutasteride and are seeking advice on managing side effects and treatment alternatives.

community Dermastamp only with carrier/essential oil blend

16 upvotes 3 years ago

A user is documenting their natural approach to treating a receding hairline using a dermastamp, essential oils (rosemary oil at 3% dilution with pumpkin seed oil), a multivitamin with vitamin D, and daily collagen shakes. They acknowledge the common recommendations of minoxidil and finasteride but prefer to test natural methods and share their results.

community Bryan Johnson's email regarding hair loss and his protocol (including why he doesn't take Fin or Dut).

in Research/Science 6 upvotes 5 months ago

Hair loss treatments include topical and oral minoxidil, low-level laser light therapy, and peptide serums. Bryan Johnson avoids finasteride and dutasteride due to potential side effects, focusing instead on his own protocol with these treatments.

community 4 months of 1mg of fin a day and 5 months of topical minoxidil

in Progress Pictures 1053 upvotes 8 months ago

Significant hair regrowth was achieved using 1mg of finasteride daily, 3ml of topical minoxidil, ketoconazole shampoo, vitamin D, and castor oil, with no side effects. Results appeared after two months, leading to discussions on treatment effectiveness and commitment.

community What is the ultimate hair regrowth protocol

29 upvotes 1 year ago

The conversation covers aggressive hair regrowth treatments like Dutasteride, Minoxidil (oral and topical), RU58841, microneedling, and ketoconazole shampoo. It also mentions PRP, laser therapy, GHK-Cu injections, and hormone therapy for maximum regrowth.

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Learn

4 / 801 results

learn Melatonin

Can melatonin cause side effects on the skin or hair? Melatonin may cause hair loss or thinning in some users, but evidence is limited.

learn Scalp Micropigmentation

Does scalp micropigmentation work on all skin tones and hair colors? Scalp micropigmentation can be customized for various skin tones and hair colors.
Is scalp micropigmentation suitable for people with sensitive skin? Providers say scalp micropigmentation suits most skin types and describe patch tests, hypoallergenic pigments and a skin consultation for sensitive skin. These are provider claims rather than independent safety evidence, and pigment reactions remain a risk.

learn retinol

How does retinol improve scalp health and prepare the skin for other hair growth treatments? Retinol improves scalp health by promoting cellular turnover and reducing congestion.

learn Hyaluronic Acid

Does hyaluronic acid really hydrate the scalp, or is it mainly for skin care? Hyaluronic acid can hydrate the scalp, but its effectiveness may vary.

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Experts

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35
SMP Specialist
Noelle Skin
Nice, France

Clinics

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All 10 clinic results →

Noelle Skin