610 citations
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April 2014 in “Nature Reviews Immunology”
The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.
Oral minoxidil may improve hair growth, reduce arterial stiffness, and prevent other health issues. Some users believe it is an effective treatment despite concerns about its effects on skin and blood.
The regimen for hair loss includes topical finasteride, clascoterone, tretinoin, minoxidil, oral saw palmetto, beta-sitosterol, vitamin D, microneedling, and anti-fungal shampoo. Expected benefits are increased hair growth and density, with considerations for potential skin irritation and interactions between treatments.
People over 35 have seen success with finasteride, minoxidil, and dutasteride for hair loss. Results vary, with some noticing improvements in hair volume and hairline, while others emphasize patience and managing expectations.
Tattooing hair loss drugs like minoxidil and dutasteride into the scalp is discussed as an alternative to daily pills, with mixed opinions on its effectiveness and convenience. Some users report positive results, but concerns about cost, potential side effects, and the procedure's discomfort are noted.