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research The Suppression of Very Long Chain Fatty Acids Is Associated with Skin Carcinogenesis

March 2020 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study suggests that the expression of VLCFA biosynthesis genes is suppressed in skin hyperplasia and cancer, which could influence keratinocyte function.

research Lgr5+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors

8 citations , July 2016 in “Oncotarget”

This study reports that actively proliferating Lgr5+ stem cells in hair follicles do not appear to drive tumor formation in experimental skin carcinogenesis.

research Keratinocyte-Expressed Podoplanin is Dispensable for Multi-Step Skin Carcinogenesis

7 citations , June 2020 in “Cells”

In this study, mice lacking podoplanin in epidermal keratinocytes showed reduced tumor cell invasion and peritumoral lymphangiogenesis, suggesting that keratinocyte-expressed podoplanin contributes to advanced stages of skin tumor progression.

research Lgr6+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors

7 citations , November 2016 in “Oncotarget”

This study found that Lgr6+ stem cells in mice are not major initiators of UV- or chemically induced skin tumors.

research MCPIP1 controls effects of myeloid cells on skin carcinogenesis and hair growth

December 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

In a mouse model study, researchers observed that the absence of MCPIP1 in myeloid cells decreased susceptibility to chemically induced skin papillomas but caused significant hair loss and skin pigmentation changes, suggesting a role for MCPIP1 in skin carcinogenesis and follicle integrity.

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Community Join

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community The Health Benefits of Head Hair

in Research/Science 19 upvotes 11 months ago

Hair provides protection against head trauma, reduces skin cancer risk, helps remove heavy metals, and aids in wound healing. The conversation emphasizes the health benefits of maintaining head hair beyond cosmetic reasons.

community My kotoconazole shampoo contain this

6 months ago

The conversation discusses the safety and use of ketoconazole shampoo for hair loss, with mentions of zinc pyrithione and selenium sulfide. Users debate the safety of these ingredients, particularly zinc pyrithione, and share opinions on regulatory differences between Europe and the US.

community On dutasteride, looking for alternatives to minoxidil

in Treatment 8 upvotes 1 month ago

The user stopped using topical minoxidil due to side effects and is now on dutasteride, seeking alternatives to minoxidil. Suggestions include oral minoxidil, foam minoxidil, KOSHINÉ, PRFM, and ketoconazole shampoo for dandruff.

community Is There Any Chance Of Cancer In Follicle Neogenesis through Microneedling?

15 upvotes 6 years ago

The conversation discusses concerns about the potential risk of cancer from creating new hair follicles through microneedling, due to stem cell division. Specific treatments mentioned include microneedling, caffeine-containing anti-hair loss shampoos, and other unspecified topicals.

community Does RU58841 potentially cause cancer?

in Research/Science 1 year ago

RU58841 may pose cancer risks due to its antiandrogen properties and lack of long-term safety data. Using it is considered a high-risk experiment with unknown potential for harm.

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Learn

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learn Epidermal Growth Factor

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Melatonin

Can melatonin cause side effects on the skin or hair? Melatonin may cause hair loss or thinning in some users, but evidence is limited.

learn Scalp Micropigmentation

Does scalp micropigmentation work on all skin tones and hair colors? Scalp micropigmentation can be customized for various skin tones and hair colors.
Is scalp micropigmentation suitable for people with sensitive skin? Providers say scalp micropigmentation suits most skin types and describe patch tests, hypoallergenic pigments and a skin consultation for sensitive skin. These are provider claims rather than independent safety evidence, and pigment reactions remain a risk.

learn retinol

How does retinol improve scalp health and prepare the skin for other hair growth treatments? Retinol improves scalp health by promoting cellular turnover and reducing congestion.

learn Hyaluronic Acid

Does hyaluronic acid really hydrate the scalp, or is it mainly for skin care? Hyaluronic acid can hydrate the scalp, but its effectiveness may vary.

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Clinics

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35
SMP Specialist
Noelle Skin
Nice, France

Noelle Skin