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5 / 1000+ resultsresearch Camellia Sinensis Seed Flavonoids Attenuate UVB-Induced Inflammation and UVA-Induced Photodamage via MAPK/NF-κB and AP-1 Pathways
This study investigated the effects of Camellia sinensis seed flavonoids (CSF) on UVB-induced inflammation and UVA-induced photodamage in human skin cells. CSF was found to significantly reduce reactive oxygen species (ROS) and inflammatory factors by inhibiting the p38/JNK and NF-κB pathways, as well as iNOS and COX-2 expression. In keratinocytes, CSF downregulated Caspase-3 and upregulated barrier proteins, while in fibroblasts, it enhanced collagen and hyaluronic acid production by modulating the AP-1 and TGF-β/Smad pathways. These findings suggest that CSF has potential as a skincare ingredient due to its anti-inflammatory, barrier-repair, and anti-photoaging properties.
research Mutations In AEC Syndrome Skin Reveal A Role For p63 In Basement Membrane Adhesion, Skin Barrier Integrity And Hair Follicle Biology
Mutations in the p63 gene affect skin adhesion, barrier integrity, and hair growth.
research Cornification
Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.
research Exosomes Derived from Adipose Tissue-Derived Mesenchymal Stem Cells for the Treatment of Dupilumab-Related Facial Redness in Patients with Atopic Dermatitis
Adipose stem cell exosomes can effectively reduce facial redness and improve skin health in atopic dermatitis patients.
research Lactate in Skin Homeostasis: Metabolism, Skin Barrier, and Immunomodulation
Lactate is vital for skin health, influencing metabolism, the skin barrier, immune responses, and has therapeutic potential for skin disorders.
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5 / 1000+ resultscommunity Countering oral minoxidil side effects by taking collagen supplements?
Oral minoxidil may deplete collagen, potentially causing skin aging. Users discuss whether taking collagen supplements can counteract this effect.
community Finasteride and “anti-aging” effects
Finasteride may help users look younger by suppressing DHT, affecting skin and hair. Users also emphasize skincare, sunscreen, and lifestyle for maintaining a youthful appearance.
community Comprehensive Microneedling Guide
Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.
community Peptides that Stop Hair Loss? | In-depth Literature Review Video
Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.
community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied
by
nkrata
in Research
830 upvotes
1 year ago Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.