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Research

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research Analysis of Skin Regeneration and Barrier-Improvement Efficacy of Polydeoxyribonucleotide Isolated from Panax Ginseng (C.A. Mey.) Adventitious Root

17 citations , October 2023 in “Molecules”

In laboratory and artificial skin model experiments, this study found that plant-derived PDRN from Korean ginseng effectively promoted skin cell regeneration and strengthened the skin barrier, suggesting a sustainable alternative to animal-derived PDRN.

research Skin Improvement Efficacy of Microspicule Cosmetics Containing Low-molecular-weight Peptide Complexes

March 2025 in “Asian Journal of Beauty and Cosmetology”

This study found that microspicule cosmetics with low-molecular-weight peptide complexes significantly improved skin whitening, pore condition, and skin barrier function over four weeks compared to a non-microspicule formulation.

research The effects of Jawoongo soap on skin improvement

1 citations , January 2024 in “Journal of Cosmetic Dermatology”

In this study, JAUN soap was found to improve skin conditions, such as moisture, elasticity, and cleansing effectiveness, without adverse reactions, suggesting its potential as a safe and effective ingredient for functional cosmetics.

research Improvement of dermal and transdermal therapies by nanocarrier-based drug delivery

January 2018 in “Refubium (Universitätsbibliothek der Freien Universität Berlin)”

In this study, researchers tested various nanocarrier characteristics and found they could enhance drug delivery to specific skin areas and immune cells, potentially improving treatments for skin conditions by targeting drugs effectively.

research Dietary sodium hyaluronate and eggshell membrane improve skin barrier function and coat health in Ragdoll cats

July 2026 in “Frontiers in Veterinary Science”

This study found that combined dietary supplementation of sodium hyaluronate and eggshell membrane was associated with various improvements in skin and coat health markers in healthy Ragdoll cats.

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Community Join

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community Dermastamping — do you use hyaluronic acid as lubricant?

3 upvotes 1 year ago

The conversation discusses using high molecular weight hyaluronic acid after microneedling to form a protective barrier, though it's considered expensive and offers marginal improvement. Users share experiences with different microneedling tools like derma rollers, dermastamps, and Dr. Pen, with some opting not to use any products on the scalp.

community Does finasteride/dutasteride reverse aging?

in Chat 45 upvotes 1 year ago

Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

community People who tolerate dut better than fin?

in Finasteride/Dutasteride 32 upvotes 1 year ago

Dutasteride may have fewer side effects than finasteride, with some users experiencing better hair maintenance. Experiences vary, with some preferring dutasteride for fewer side effects, while others see no significant hair improvement.

community 25M | 14-month FUE update + regimen (looking for advice on improving crown density)

in Progress Pictures 2 upvotes 1 month ago

A 25-year-old male seeks advice on improving crown density after two hair transplants and shares his regimen, which includes derma stamping, minoxidil, dutasteride, pumpkin seed oil, vitamins, and ketoconazole shampoo. Feedback suggests reducing minoxidil dosage, derma stamping frequency, and ketoconazole use to prevent skin damage.

community 2024 vs today. Dutasteride 0.5mg and 5mg oral minoxidil

in Progress Pictures 91 upvotes 6 months ago

The user experienced significant hair regrowth using 0.5mg dutasteride and 5mg oral minoxidil, with fewer side effects compared to finasteride. They noticed improvements in hair thickness and hairline, despite intermittent use of performance-enhancing substances.

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Learn

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learn Tretinoin

Vitamin A retinoid cream, prescribed for acne

learn oleic acid

Is Oleic Acid safe to apply directly to the scalp, or should it be used in a formula? Oleic acid loosens the skin's lipid barrier, and studies link it to flaking in dandruff-prone people. Its effects on the scalp, neat or in formulas, have not been tested in trials.

learn Linoleic Acid

Does linoleic acid reduce scalp irritation that can worsen hair loss? Linoleic acid is part of the skin barrier, but no human study shows that applying it reduces scalp irritation or slows hair loss.
How does linoleic acid work on the scalp when used in shampoos or oils? Linoleic acid is part of the skin's lipid barrier, and lab studies link it to hair-growth signals. No human trial shows that shampoos or oils containing it improve hair growth.

learn Jojoba oil

Can jojoba oil reduce scalp irritation or dryness that makes hair fall out more easily? Jojoba oil is used to moisturise dry skin, and a review of plant oils describes it as a possible option for a damaged skin barrier. No study shows that it reduces scalp irritation or hair loss.

learn Glycerin

What role does glycerin play in scalp hydration and overall hair health? Glycerin is a humectant that draws water into the outer skin layer; small skin studies show better hydration and barrier repair, but the scalp evidence comes only from multi-ingredient products.

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Clinics

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Experts

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SMP Specialist
Noelle Skin
Nice, France

Noelle Skin