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Glossary Sjogren's syndrome

autoimmune disorder causing dry eyes and mouth

Sjogren's syndrome, also known as Sicca syndrome, is an autoimmune disorder where the body's immune system mistakenly attacks its own moisture-producing glands. This leads to symptoms such as dry eyes and dry mouth, and it can also affect other organs and systems, including the skin, joints, and nervous system.

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Unusual Systemic Lupus Erythematosus/Sjogren's Syndrome Phenotype in a Patient with a TNFAIP3 Gene Mutation

research SAT0200 UNUSUAL SYSTEMIC LUPUS ERYTHEMATOSUS/SJOEGREN'S SYNDROME PHENOTYPE IN A PATIENT WITH A TNFAIP3 GENE MUTATION

June 2019

This case report details a child with a specific TNFAIP3 mutation manifesting as a severe SLE/SS phenotype, expanding the known phenotype for this genetic variant.

research Sjögren's Syndrome in Scurvy

55 citations , May 1970 in “New England Journal of Medicine”

This study found that scurvy is associated with the development of Sjögren's syndrome symptoms, which resolved with ascorbic acid repletion.

research Frontal fibrosing alopecia in association with Sjögren's syndrome: more than a simple coincidence

12 citations , October 2016 in “Anais Brasileiros de Dermatologia”

This review discusses the increasing reports of frontal fibrosing alopecia, a form of scarring alopecia, and its potential link to autoimmune disorders, but reports no new clinical results.

research Triple-Negative Sjogren’s Syndrome and Recurrent Pneumothorax: An Uncommon Presentation of Autoimmune Disease

2 citations , July 2022 in “Cureus”

This case report describes a rare patient with Sjogren's syndrome who experienced recurrent pneumothorax, resolved through surgical intervention, highlighting pneumothorax as an unusual complication of the condition.

research Novel Mutation in Sjögren-Larsson Syndrome Is Associated With Divergent Neurologic Phenotypes

15 citations , October 2012 in “Journal of child neurology”

In this study, two unrelated Honduran patients with Sjögren-Larsson syndrome had the same genetic mutation but displayed different disease severities, suggesting that factors beyond the ALDH3A2 mutation influence clinical outcome.

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