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research Genetic Fate Mapping Using Site-Specific Recombinases

29 citations , January 2010 in “Methods in Enzymology”

This review discusses five genetic fate mapping methods used to study cell behaviors during development and regeneration, detailing the necessary tools and considerations without reporting new experimental results.

Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Regeneration After Facial Nerve Injury

research Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Also Regeneration after Facial Nerve Injury

6 citations , February 2022 in “The journal of neuroscience/The Journal of neuroscience”

This study observed that deleting PTEN in mouse facial motoneurons enhanced peripheral axon regeneration but also led to physiological changes and potential hyperplasia in older mice.

research Development of novel wound dressing based on elastin-like recombinamers for skin regeneration

January 2024

This study found that elastin-like recombinamer (ELR) wound dressings promote tissue regeneration and stability without rejection in ex vivo and in vivo models, indicating potential for hard-to-heal wound treatment.

Site of Beige and Leaden Pigment Gene Expression Determined by Recombinant Embryonic Skin Grafts and Aggregation Mouse Chimaeras Employing Sash Homozygotes

research Site of beige (bg) and leaden (ln) pigment gene expression determined by recombinant embryonic skin grafts and aggregation mouse chimaeras employing sash (W^sh) homozygotes

7 citations , October 1985 in “Genetics Research”

This study found that in chimaeric mice models, the pigment distribution and pattern were influenced by the sash genotype, demonstrating the melanocyte-autonomous nature of the beige and leaden loci.

research A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing

9 citations , October 2022 in “Nature Communications”

In this study, researchers developed a new photoactivatable Cre recombinase mouse model, DiLiCre, which allows precise light-induced genetic modifications and cell tracing, demonstrating its effectiveness for advancing biological and biomedical research.

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community Which compounds in Saw Palmetto are actually beneficial?

4 upvotes 1 year ago

Saw palmetto's fatty acids, particularly lauric and linoleic acids, inhibit enzymes linked to hair loss, while sterols like beta-sitosterol are less effective due to poor absorption. The conversation questions which specific compounds in saw palmetto contribute to its anti-androgenic effects.

community Kintor starts a new Phase 3 for Pyri... (1+ year)

16 upvotes 3 years ago

The conversation discusses Kintor's initiation of a new Phase 3 trial to assess the long-term safety of Pyrilutamide (KX-826) for hair loss, which will last 52 weeks. Specific treatments mentioned include Pyrilutamide.

community DIY GHK-CU hair growth serum, help

4 upvotes 2 months ago

OP plans to make a DIY GHK-CU hair growth serum using hyaluronic acid and seeks advice on which Ordinary serum to use. Users discuss the effectiveness of GHK-CU, AHK-CU, and other products for hair growth, with some recommending specific concentrations and sharing personal experiences.

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