36 citations
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February 2016 in “British journal of pharmacology” This study found that SIRT1 negatively regulates fibroblast activation and excessive scar formation, suggesting it may be a promising drug target for treating hypertrophic scars.
August 2015 in “Free Radical Biology and Medicine” This study explores the correlation between sirtuins' expression, histone deacetylation, and redox status in young and old monozygotic twins to understand their role in age-related mechanisms.
July 2025 in “Journal of Investigative Dermatology” 9 citations
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March 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” This symposium reviewed various advances in understanding and potentially reversing skin aging, with no new experimental results reported.
6 citations
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May 2020 in “Nutrients” This review discusses the effects of calorie restriction on skin aging, highlighting its potential to benefit skin health by reducing age-related and photo-induced changes, although the impact of certain diets remains unexplored.