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research Mutation-Specific siRNA Knockdown of GJB2: Potential Gene Therapy for Keratitis-Ichthyosis-Deafness Syndrome

April 2017 in “Journal of Investigative Dermatology”

Targeted siRNA therapy may be a promising treatment for KID syndrome by reducing mutant gene expression and improving cell communication.

research Notch1 Signaling Regulates Wound Healing by Changing the Characteristics of Epidermal Stem Cells

6 citations , January 2016 in “Journal of Stem Cell Research & Therapy”

Notch1 signaling is crucial for improving wound healing and skin regeneration by affecting stem cell behavior.

research Cholesterol Homeostasis in Hair Follicle Keratinocytes Is Disrupted by Impaired ABCA5 Activity

June 2023 in “Biochimica and biophysica acta. Molecular and cell biology of lipids”

Impaired ABCA5 activity disrupts cholesterol balance in hair follicle cells, affecting hair growth.

research Twist2 Contributes to Skin Regeneration and Hair Follicle Formation in Mouse Fetuses

March 2024 in “Research Square (Research Square)”

Twist2 is essential for proper skin healing and hair growth in developing mice.

research Dermal Papilla Cell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1

February 2023 in “International Journal of Molecular Sciences”

Exosomes from skin cells can boost hair growth by stimulating a gene called LEF1.

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Community Join

5 / 13 results

community Sandalore: a scientific homemade approch

20 upvotes 7 years ago

The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.

community Concerns about CosmeRNA safety mechanisms

in Treatment 3 upvotes 2 years ago

Concerns about CosmeRNA safety mechanisms and potential side effects. Discussion includes comparisons to Fluridil and questions about nanoparticle specificity and siRNA stability.

community Since there is so much hype for cosmeRNA and HMI-115...

in Chat 45 upvotes 2 years ago

Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.

community What new hair-loss treatments actually look exciting right now (Oct 2025)

in Research/Science 165 upvotes 4 weeks ago

New hair loss treatments include Breezula, PP405, ET-02, KX-826, GT20029, VDPHL01, and CosmeRNA, with some showing promise in reactivating stem cells and reversing greying. Breezula and VDPHL01 are highlighted as potential add-ons or alternatives to current treatments like finasteride and minoxidil.

community cosmeRNA finally now it's pyrilutamide turn

in Chat 51 upvotes 2 years ago

Hair loss treatments discussed include cosmeRNA, minoxidil, finasteride, RU58841, and pyrilutamide. Users debate effectiveness, side effects, and upcoming treatments, with some expressing skepticism and others optimism.

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